PEDIATRIC H3K27M MUTANT DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG) SHOWS ROBUST RESPONSE TO IMIPRIDONE BASED COMBINATION THERAPY

被引：0
|
作者：
Borsuk, Robyn [1 ]
Zhou, Lanlan [2 ,3 ]
Chang, Wen-i [1 ]
Zhang, Yiqun [2 ,3 ]
Prabhu, Varun [4 ]
Allen, Joshua [4 ]
Tapinos, Nikos [1 ]
Lulla, Rishi [1 ]
El-Deiry, Wafik [2 ,3 ]
机构：
[1] Brown Univ, Warren Alpert Med Sch, Providence, RI 02912 USA
[2] Brown Univ, Providence, RI 02912 USA
[3] Lifespan Canc Inst, Providence, RI 02912 USA
[4] Oncoceutics Inc, Philadelphia, PA USA
来源：
NEURO-ONCOLOGY | 2021年 / 23卷
关键词：
D O I：
10.1093/neuonc/noab090.106
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
HGG-42
引用
收藏
页码：26 / 26
页数：1
相关论文
共 50 条
  • [1] PRECLINICAL EVALUATION OF IMIPRIDONE-BASED COMBINATION THERAPIES IN PEDIATRIC H3K27M MUTANT DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)
    Borsuk, Robyn
    Zhou, Lanlan
    Zhang, Yiqun
    Prabhua, Varun
    Allen, Joshua
    Oster, Wolfgang
    Tapinos, Nikos
    Lulla, Rishi R.
    El-Deiry, Wafik
    NEURO-ONCOLOGY, 2020, 22 : 299 - 299
  • [2] Synergistic imipridone-based drug combinations for treatment of pediatric H3K27M mutant diffuse intrinsic pontine glioma (DIPG)
    Borsuk, Robyn
    Zhou, Lanlan
    Zheng, Yiqun
    Prabhu, Varun
    Allen, Joshua
    Tapinos, Nikos
    Lulla, Rishi
    Wafik, El-Deiry
    FASEB JOURNAL, 2021, 35
  • [3] Response to novel imipridone combination therapies targeting H3K27M mutant diffuse midline glioma (DMG).
    Borsuk, Robyn
    Zhou, Lanlan
    Zhang, Yiqun
    Prabhu, Varun V.
    Allen, Joshua E.
    Tapinos, Nikos
    Lulla, Rishi
    El-Deiry, Wafik S.
    CANCER RESEARCH, 2021, 81 (13)
  • [4] Developing H3K27M mutant selective radiosensitization strategies in diffuse intrinsic pontine glioma
    Parsels, Leslie A.
    Wahl, Daniel
    Koschmann, Carl
    Morgan, Meredith A.
    Zhang, Qiang
    NEOPLASIA, 2023, 37
  • [5] Novel imipridone combination therapies targeting oncohistone H3K27M mutant diffuse midline glioma (DMG)
    Borsuk, Robyn
    Zhou, Lanlan
    Lulla, Rishi
    El-Deiry, Wafik
    CANCER RESEARCH, 2020, 80 (16)
  • [6] Pediatric Non-Pontine Diffuse Midline Glioma H3K27M Mutant: A Monoinstitutional Experience
    Schiavello, E.
    Biassoni, V.
    Gattuso, G.
    Pecori, E.
    Diletto, B.
    Gandola, L.
    Massimino, M.
    PEDIATRIC BLOOD & CANCER, 2019, 66 : S193 - S194
  • [7] PEDIATRIC NON-PONTINE DIFFUSE MIDLINE GLIOMA H3K27M MUTANT: A MONOINSTITUTIONAL EXPERIENCE
    Schiavello, E.
    Biassoni, V.
    De Cecco, L.
    Pecori, E.
    Filippo, S.
    Gandola, L.
    Massimino, M.
    NEURO-ONCOLOGY, 2021, 23 : 24 - 24
  • [8] PEDIATRIC NON-PONTINE DIFFUSE MIDLINE GLIOMA H3K27M MUTANT: A MONOINSTITUTIONAL EXPERIENCE
    Schiavello, Elisabetta
    Biassoni, Veronica
    Pecori, Emilia
    Diletto, Barbara
    Antonelli, Manila
    Modena, Piergiorgio
    Gandola, Lorenza
    Massimino, Maura
    NEURO-ONCOLOGY, 2018, 20 : 57 - 57
  • [9] A circular mRNA vaccine expressing the neoepitope H3K27M for diffuse intrinsic pontine glioma
    Wirojjananuwat, Rujeerada
    Pakiranay, Chatbenja
    Anurathapan, Usanarat
    Hongeng, Suradej
    Wongtrakoongate, Patompon
    CANCER SCIENCE, 2025, 116 : 439 - 439
  • [10] H3K27M mutant diffuse midline glioma: a case report
    Luo, Y.
    Zeng, L.
    Xie, X-Q
    Wang, F.
    Liu, Y-Z
    Kang, J-B
    Li, X-F
    Wu, D-B
    Qu, B-L
    EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES, 2020, 24 (05) : 2579 - 2584
12345