ASSESSMENT OF PATIENT-REPORTED OUTCOMES (PROs) IN PATIENTS WITH NON-ALCOHOLIC STEATOHEPATITIS (NASH) TREATED WITH OBETICHOLIC ACID (OCA): RESULTS FROM REGENERATE PHASE 3 CLINICAL TRIAL

被引：0

作者：

Younossi, Zobair M. ^{[1
,2
,3
]}

Stepanova, Maria ^{[4
]}

Nader, Fatema ^{[4
]}

Loomba, Rohit ^{[5
]}

Anstee, Quentin M. ^{[6
]}

Ratziu, Vlad ^{[7
]}

Harrison, Stephen A. ^{[8
]}

Sanyal, Arun J. ^{[9
]}

Trotter, James F. ^{[10
]}

Sheikh, Muhammad Y. ^{[11
]}

Montano-Loza, Aldo J. ^{[12
]}

Olveria, Antonio ^{[13
]}

Stinton, Laura M. ^{[14
]}

Sheridan, David A. ^{[15
,16
]}

Vargas, Victor ^{[17
]}

Gluud, Lise L. ^{[18
]}

Safadi, Rifaat ^{[19
]}

Schattenberg, Joern ^{[20
]}

Khalili, Mandana ^{[21
]}

Orr, David W. ^{[22
]}

Peck-Radosavljevic, Markus ^{[23
]}

Allison, Michael E. ^{[24
]}

Cawkwell, Gail ^{[25
]}

Wong, Bruce ^{[25
]}

Bedossa, Pierre ^{[26
]}

Goodman, Zachary D. ^{[1
,27
]}

Rinella, Mary E. ^{[28
]}

机构：

[1] Inova Hlth Syst, Betty & Guy Beatty Ctr Integrated Res, Falls Church, VA USA

[2] Inova Fairfax Hosp, Ctr Liver Dis, Falls Church, VA USA

[3] Inova Fairfax Hosp, Dept Med, Falls Church, VA USA

[4] Ctr Outcomes Res Liver Dis, Washington, DC USA

[5] Univ Calif San Diego, NAFLD Res Ctr, San Diego, CA 92103 USA

[6] Newcastle Univ, Newcastle Upon Tyne, Tyne & Wear, England

[7] AP HP, Paris, France

[8] Univ Oxford, Oxford, England

[9] VCU, Richmond, VA USA

[10] Texas Digest Dis Consultants, Clin Res, Dallas, TX USA

[11] Fresno Clin Res Ctr, Fresno, CA USA

[12] Univ Alberta, Edmonton, AB, Canada

[13] Hosp Univ, Madrid, Spain

[14] Univ Calgary, Med, Calgary, AB, Canada

[15] Plymouth Hosp NHS Trust, Plymouth, Devon, England

[16] Plymouth Univ, Plymouth, Devon, England

[17] Hosp Valle De Hebron, Barcelona, Spain

[18] Copenhagen Univ Hosp Hvidore, Hvidovre, Denmark

[19] Hadassah Hebrew Univ Med Ctr, Hadassah Med Org, Jerusalem, Israel

[20] Univ Med Ctr Mainz, Dept Med, Mainz, Germany

[21] Univ Calif San Francisco, San Francisco, CA 94143 USA

[22] Auckland City Hosp, Auckland, New Zealand

[23] Med Univ Wien, Vienna, Austria

[24] Addenbrookes Hosp, Dept Hepatol, Cambridge, England

[25] Intercept Pharmaceut, New York, NY USA

[26] Hop Beaujon, Clichy, France

[27] Inova Fairfax Hosp, Falls Church, VA USA

[28] Feinberg Sch Med, Chicago, IL USA

来源：

HEPATOLOGY | 2019年 / 70卷

关键词：

D O I：

暂无

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

2324

引用

页码：1366A / 1368A

页数：3

共 50 条

[1] THE IMPACT OF PRURITUS ON PATIENT-REPORTED OUTCOMES (PROs) IN PATIENTS WITH NON-ALCOHOLIC STEATOHEPATITIS (NASH) TREATED WITH OBETICHOLIC ACID (OCA)
Younossi, Zobair M.
Stepanova, Maria
Nader, Fatema
Loomba, Rohit
Anstee, Quentin M.
Ratziu, Vlad
Harrison, Stephen A.
Sanyal, Arun J.
George, Jacob
Beckebaum, Susanne
Orr, David W.
Mazzella, Giuseppe
Vargas, Victor
Gluud, Lise L.
Safadi, Rifaat
Trotter, James F.
Behari, Jaideep
Sheridan, David A.
Sheikh, Muhammad Y.
Cawkwell, Gail
Wong, Bruce
Bedossa, Pierre
Goodman, Zachary D.
Rinella, Mary E.
HEPATOLOGY, 2019, 70 : 39A - 40A
[2] PATIENT-REPORTED OUTCOMES (PROs) IN PATIENTS WITH NON-ALCOHOLIC STEATOHEPATITIS (NASH) AND COMPENSATED CIRRHOSIS (CC): DATA FROM THE STELLAR-4 PHASE 3 CLINICAL TRIAL
Younossi, Zobair M.
Stepanova, Maria
Nader, Fatema
Romero-Gomez, Manuel
Okanoue, Takeshi
Trauner, Michael H.
Myers, Robert P.
Djedjos, Stephen
Harrison, Stephen A.
Goodman, Zachary D.
HEPATOLOGY, 2019, 70 : 1119A - 1120A
[3] OBETICHOLIC ACID (OCA) IMPROVES NON-INVASIVE MARKERS OF FIBROSIS IN PATIENTS WITH NON-ALCOHOLIC STEATOHEPATITIS (NASH): A SECONDARY ANALYSIS OF THE PHASE 3 REGENERATE STUDY
Anstee, Q. M.
Harrison, S.
Sanyal, A. J.
Ratziu, V.
Rinella, M.
Younossi, Z. Y.
Boursier, J.
Francque, S.
Geerts, A.
Petta, S.
Bugianesi, E.
Romero-Gomez, M.
Schattenberg, J. M.
Sarkar, S.
Bonacini, M.
Yataco, M.
Porayko, M.
Siddique, A.
Dufour, J.
Ferro, T.
Venugopal, A.
Zaru, L.
Shringarpure, R.
Macconell, L.
Goodman, Z.
Loomba, R.
DIGESTIVE AND LIVER DISEASE, 2020, 52 : S163 - S163
[4] Obeticholic acid (OCA) improves non-invasive markers of fibrosis in patients with non-alcoholic steatohepatitis (NASH): a secondary analysis of the phase 3 Regenerate study
Anstee, Q. M.
Harrison, S.
Sanyal, Arun J.
Ratziu, V.
Rinella, M.
Younossi, Z. Y.
Boursier, J.
Francque, S.
Geerts, A.
Petta, S.
Bugianesi, E.
Romero-Gomez, M.
Schattenberg, J. M.
Sarkar, S.
Bonacini, M.
Yataco, M.
Porayko, M.
Siddique, A.
Dufour, J.
Ferro, T.
Venugopal, A.
Zaru, L.
Shringarpure, R.
MacConell, L.
Goodman, Z.
Loomba, R.
DIGESTIVE AND LIVER DISEASE, 2020, 52 : E41 - E42
[5] OBETICHOLIC ACID (OCA) IMPROVES NON-INVASIVE MARKERS OF FIBROSIS IN PATIENTS WITH NON-ALCOHOLIC STEATOHEPATITIS (NASH): A SECONDARY ANALYSIS OF THE PHASE 3 REGENERATE STUDY
Anstee, Quentin M.
Harrison, Stephen A.
Sanyal, Arun J.
Ratziu, Vlad
Rinella, Mary E.
Younossi, Zobair M.
Boursier, Jerome
Francque, Sven M.
Geerts, Anja
Petta, Salvatore
Bugianesi, Elisabetta
Romero-Gomez, Manuel
Schattenberg, Joern
Sarkar, Souvik
Bonacini, Maurizio
Yataco, Maria Luisa
Porayko, Michael K.
Siddique, Asma
Dufour, Jean-Francois
Ferro, Tom
Venugopal, Aditya
Zaru, Luna
Shringarpure, Reshma
MacConell, Leigh
Goodman, Zachary D.
Loomba, Rohit
HEPATOLOGY, 2019, 70 : 1030A - 1032A
[6] Improvement of hepatic fibrosis in patients with non-alcoholic steatohepatitis treated with selonsertib is associated with improvement of patient-reported outcomes (PROS)
Younossi, Z. M.
Stepanova, M.
Goodman, Z.
Lawitz, E.
Charlton, M.
Loomba, R.
Hunt, S.
JOURNAL OF HEPATOLOGY, 2017, 66 (01) : S53 - S53
[7] Improvements of Hepatic Fibrosis and Hepatic Collagen Deposition in Non-Alcoholic Steatohepatitis (NASH) Treated with Selonsertib are Associated with Improvement of Patient-Reported Outcomes (PROs)
Younossi, Zobair M.
Stepanova, Maria
Goodman, Zachary D.
Lawitz, Eric
Charlton, Michael R.
Loomba, Rohit
Myers, Robert P.
Subramanian, Mani
McHutchison, John G.
Hunt, Sharon
HEPATOLOGY, 2017, 66 : 1170A - 1171A
[8] Severe Impairment of Patient-Reported Outcomes in Patients with Advanced Fibrosis Due to Non-Alcoholic Steatohepatitis (NASH)
Younossi, Zobair M.
Stepanova, Maria
Anstee, Quentin M.
Lawitz, Eric J.
Wong, Vincent Wai Sun
Kersey, Kathryn
Li, Georgia
Subramanian, Mani
Myers, Robert P.
Djedjos, Stephen
Okanoue, Takeshi
Trauner, Michael H.
Harrison, Stephen A.
Goodman, Zachary D.
Romero-Gomez, Manuel
HEPATOLOGY, 2018, 68 : 958A - 959A
[9] CLINICAL AND PATIENT-REPORTED OUTCOMES DATA FOR PATIENTS WITH NON-ALCOHOLIC FATTY LIVER DISEASE (NAFLD) AND NON-ALCOHOLIC STEATOHEPATITIS (NASH) ACROSS THE WORLD: DATA FROM THE GLOBAL NASH REGISTRY
Younossi, Zobair M.
Yu, Ming-Lung
El Kassas, Mohamed
Esmat, Gamal
Yilmaz, Yusuf
Fernandez, Marlen Castellanos
Duseja, Ajay K.
Isakov, Vasily A.
Buti, Maria
Mendez-Sanchez, Nahum
Papatheodoridis, George V.
Chan, Wah Kheong
George, Jacob
Bugianesi, Elisabetta
Romero-Gomez, Manuel
Roberts, Stuart K.
Younes, Ziad
Wong, Vincent Wai-Sun
Fan, Jian-Gao
Eguchi, Yuichiro
Gordon, Stuart C.
Ahmed, Aijaz
Ong, Janus
Jacobson, Ira M.
Rinella, Mary E.
Hamid, Saeed S.
Ziayee, Mariam
Younossi, Issah
Lam, Brian P.
Arrese, Marco
Nader, Fatema
Racila, Andrei
Henry, Linda
Stepanova, Maria
HEPATOLOGY, 2019, 70 : 749A - 750A
[10] Improvement of hepatic fibrosis and patient-reported outcomes in non-alcoholic steatohepatitis treated with selonsertib
Younossi, Zobair M.
Stepanova, Maria
Lawitz, Eric
Charlton, Michael
Loomba, Rohit
Myers, Robert P.
Subramanian, Mani
McHutchison, John G.
Goodman, Zachary
LIVER INTERNATIONAL, 2018, 38 (10) : 1849 - 1859

← 1 2 3 4 5 →