Reaction of organometallic compounds with polyfluorinated benzene derivatives:: Synthesis of 1-[3-(2,4-difluorobenzoyl)-phenyl]-propan-1-one

被引：2

作者：

Martí, J ^{[1
]}

Ballart, B ^{[1
]}

Velasco, D ^{[1
]}

López-Calahorra, F ^{[1
]}

机构：

[1] Univ Barcelona, Dept Quim Organ, E-08028 Barcelona, Spain

来源：

SYNTHETIC COMMUNICATIONS | 2000年 / 30卷 / 16期

关键词：

D O I：

10.1080/00397910008087450

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The abnormally high acidity of the aromatic proton placed between two fluorine atoms in the benzene ring renders the compounds with this substitution pattern incompatible with the conventional organometallic compounds in synthetic processes. The synthesis of 1-[3-(2,4-difluorobenzoyl)phenyl]-propan-1-one via the Stille reaction is reported as a remedy.

引用

页码：3023 / 3030

页数：8

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