Current Neoadjuvant Strategies in Rectal Cancer

被引：38
|
作者：
Julien, Lucas A. [1 ]
Thorson, Alan G. [1 ,2 ,3 ]
机构：
[1] Colon & Rectal Surg Inc, Omaha, NE USA
[2] Univ Nebraska, Omaha, NE 68182 USA
[3] Creighton Univ, Omaha, NE 68178 USA
来源：
JOURNAL OF SURGICAL ONCOLOGY | 2010年 / 101卷 / 04期
关键词：
rectal cancer; neoadjuvant therapy; chemotherapy; radiation therapy; review; SYNCHRONOUS LIVER METASTASES; PREOPERATIVE CHEMORADIATION; COLORECTAL-CARCINOMA; MESORECTAL EXCISION; IMPROVED SURVIVAL; COMPLETE RESPONSE; RESECTION; RADIOTHERAPY; CHEMOTHERAPY; SURGERY;
D O I：
10.1002/jso.21480
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Treatment modalities in rectal cancer have undergone a slow, evolutionary transition over the past 30 years. More recently, contemporary descriptions of advanced preoperative chemotherapy and radiation schema have led to a rapid revolution in the management of this disease. In this review we focus on current evidence-based neoadjuvant strategies used in the treatment of locally advanced rectal cancer and metastatic rectal disease. Finally, we provide a foundation for discussion of still unresolved issues. J Surg. Oncol. 2010;101:321-326. (C) 2010 Wiley-Liss, Inc.
引用
收藏
页码：321 / 326
页数：6
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