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Zhongshan Univ, Affiliated Hosp 1st, Dept Obstet & Gynecol, Ctr Res Reprod, Guangzhou 510080, Guangdong, Peoples R China Zhongshan Univ, Affiliated Hosp 1st, Dept Obstet & Gynecol, Ctr Res Reprod, Guangzhou 510080, Guangdong, Peoples R China