Lipase-mediated diastereoselective and enantioselective acetylations of 3-substituted cyclohexanols

被引：12
|
作者：
Tanikaga, R [1 ]
Morita, A [1 ]
机构：
[1] Ritsumeikan Univ, Fac Sci & Engn, Dept Biosci & Biotechnol, Shiga 525, Japan
来源：
TETRAHEDRON LETTERS | 1998年 / 39卷 / 07期
关键词：
D O I：
10.1016/S0040-4039(97)10705-5
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Lipase-mediated acetylation of four diastereomeric and enatiomeric isomers of 3-substituted cyclohexanols 2 has led to an efficient resolution to provide a single stereoisomer, (1R,3S)-cyclohexyl acetate (1R,3S)-3 in a high enantiomeric excess. (C) 1998 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：635 / 638
页数：4
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