Targeted therapy of hormone receptor-positive breast cancer harboring PIK3CA and AKT1 genetic aberrations

被引:0
|
作者
Shariati, Maryam
Evans, Kurt W.
Scott, Stephen M.
Chen, Huiqin
Meric-Bernstam, Funda
机构
关键词
D O I
10.1158/1538-7445.AM2017-135
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
135
引用
收藏
页数:2
相关论文
共 50 条
  • [1] PIK3CA and AKT1 mutations are independent in invasive breast cancer
    Moynahan, M. E.
    Heguy, A.
    Drobnjak, M.
    Traina, T.
    Howard, J.
    Patil, S.
    Gerald, W.
    Solit, D.
    Hudis, C.
    CANCER RESEARCH, 2009, 69 (02) : 119S - 120S
  • [2] Somatic mutations of PIK3CA and AKT1 in Japanese breast cancer
    Shimoi, T.
    Hamada, A.
    Kitamura, Y.
    Nishijo, T.
    Shimomura, A.
    Shimizu, C.
    Yoshida, M.
    Kinoshita, T.
    Fujiwara, Y.
    Tamura, K.
    ANNALS OF ONCOLOGY, 2016, 27
  • [3] PIK3CA mutation inhibition in hormone receptor-positive breast cancer: time has come
    De Mattos-Arruda, Leticia
    ESMO OPEN, 2020, 5 (04)
  • [4] Epigenetic Therapy in Hormone Positive Breast Cancer: The Role of PIK3CA
    Blawski, Ryan
    Toska, Eneda
    CURRENT BREAST CANCER REPORTS, 2025, 17 (01)
  • [5] Prevalence of somatic PIK3CA mutations in hormone receptor-positive metastatic breast cancer: The Indian experience
    Goel, Aastha
    Gogia, Ajay
    Mathur, Sandeep
    Sasi, Archana
    Batra, Atul
    Deo, S. V. S.
    Tanwar, Pranay
    Prasad, Chandra Prakash
    JOURNAL OF CLINICAL ONCOLOGY, 2024, 42 (16)
  • [6] Mucinous breast carcinomas lack PIK3CA and AKT1 mutations
    Kehr, Elizabeth L.
    Jorns, Julie M.
    Ang, Daphne
    Warrick, Andrea
    Neff, Tanaya
    Degnin, Michelle
    Lewis, Rebecca
    Beadling, Carol
    Corless, Christopher L.
    Troxell, Megan L.
    HUMAN PATHOLOGY, 2012, 43 (12) : 2207 - 2212
  • [7] Molecular Analysis of PIK3CA in Metastatic Hormone Receptor-Positive Breast Cancer in Chile: Clinical and Pathological Insights
    Araya, Carla
    Mino, Barbara
    Le Cerf, Patricio
    Gaete, Fancy
    Armisen, Ricardo
    Carvajal-Hausdorf, Daniel E.
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2024, 25 (22)
  • [8] Clinical significance of PIK3CA, AKT1, and ESR1 mutation in plasma cell-free DNA from estrogen receptor-positive breast cancer patients
    Takeshita, Takashi
    Tomiguchi, Mai
    Sueta, Aiko
    Yamamoto-Ibusuki, Mutsuko
    Yamamoto, Yutaka
    Iwase, Hirotaka
    CANCER RESEARCH, 2018, 78 (13)
  • [9] Regulation of tumor angiogenesis by PIK3CA and AKT1 in ovarian cancer
    Xia, Chang
    Meng, Qiao
    Jiang, Bing-Hua
    CANCER RESEARCH, 2006, 66 (08)
  • [10] PIK3CA Mutations in Hormone Receptor-Positive Breast Cancers PIKing Biomarkers to Inform Adjuvant Endocrine Therapy Decisions
    Stearns, Vered
    Park, Ben Ho
    JAMA ONCOLOGY, 2018, 4 (10) : 1330 - 1332