Go-Dact: A Phase 3b Randomized Double-Blind Placebo-Controled Proof-Of-Concept Trial, of Golimumab Plus Methotrexate (MTX) versus MTX Monotherapy, in Improving Dactylitis, in MTX Naive Psoriatic Arthritis Patients

被引：0

作者：

Vieira-Sousa, Elsa ^{[1
]}

Alves, Pedro ^{[2
]}

Rodrigues, Ana Maria ^{[3
]}

Teixeira, Filipa ^{[4
]}

Tavares-Costa, Jose ^{[5
]}

Bernardo, Alexandra ^{[6
]}

Pimenta, Sofia ^{[6
]}

Pimentel-Santos, Fernando ^{[7
]}

Gomes, Joao Lagoas ^{[8
,9
]}

Aguiar, Renata ^{[10
]}

Pinto, Patricia ^{[11
]}

Videira, Taciana ^{[11
]}

Catita, Cristina ^{[12
]}

Santos, Helena ^{[13
]}

Borges, Joana ^{[14
]}

Sequeira, Graca ^{[15
]}

Ribeiro, Celia ^{[15
]}

Teixeira, Lidia ^{[16
]}

Avila-Ribeiro, Pedro ^{[17
,18
,19
]}

Martins, Fernando M. ^{[20
]}

Canhao, Helena ^{[21
]}

Ribeiro, Ruy M. ^{[22
]}

Fonseca, Joao Eurico ^{[17
,18
,19
]}

机构：

[1] Univ Lisbon, Lisbon Acad Med Ctr, Fac Med,Rheumatol & Metab Bone Dis,Hosp Santa Mar, Ctr Hosp Lisboa Norte EPE,Rheumatol Res Unit,Inst, Lisbon, Portugal

[2] CHLC, Radiol Dept, Lisbon, Portugal

[3] Ctr Acad Med Lisboa, HSEIT Ilha Terceira Acores & FMUL, Rheumatol Unit, Lisbon, Portugal

[4] ULSAM, Rheumatol Dept, Ponte do Lima, Portugal

[5] ULSAM, Ponte do Lima, Portugal

[6] CHSJ, Rheumatol Dept, Porto, Portugal

[7] CHLO, Hosp Egas Moniz, NOVA Med Sch, CEDOC, Lisbon, Portugal

[8] Ctr Hosp Lisboa Ocident, Hosp Egas Moniz, Rheumatol Dept, Lisbon, Portugal

[9] NOVA Med Sch, Fac Ciencias Med, CEDOC, Lisbon, Portugal

[10] CHBV, Rheumatol Dept, Aveiro, Portugal

[11] CHVNG, Rheumatol Dept, Vila Nova De Gaia, Portugal

[12] Hosp Particular Algarve, Faro, Portugal

[13] IPR, Lisbon, Portugal

[14] Inst Portugues Reumatol, Lisbon, Portugal

[15] CHA, Rheumatol Unit, Faro, Portugal

[16] HGO, Rheumatol Dept, Almada, Portugal

[17] Ctr Hosp Univ Lisboa Norte, Hosp Santa Maria, Rheumatol & Bone Dis Dept, Lisbon, Portugal

[18] Univ Lisbon, Fac Med, Inst Med Mol, Unidade Invest Reumatol, Lisbon, Portugal

[19] Ctr Acad Med Lisboa, Lisbon, Portugal

[20] Portuguese Soc Rheumatol, Lisbon, Portugal

[21] NOVA Med Sch, EpiDoC Unit, CEDOC, Lisbon, Portugal

[22] FMUL, Lab Biomatemat, Lisbon, Portugal

来源：

ARTHRITIS & RHEUMATOLOGY | 2019年 / 71卷

关键词：

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

2876

引用

页数：2

共 41 条

[1] GO-DACT: A RANDOMIZED DOUBLE-BLIND PLACEBO-CONTROLED PROOF-OF-CONCEPT TRIAL OF GOLIMUMAB PLUS METHOTREXATE (MTX) VERSUS MTX MONOTHERAPY, IN IMPROVING DACTYLITIS, IN MTX NAIVE PSORIATIC ARTHRITIS PATIENTS
Vieira-Sousa, Elsa
Alves, Pedro
Rodrigues, Ana Maria
Teixeira, Filipa
Tavares-Costa, Jose
Bernardo, Alexandra
Pimenta, Sofia
Dos Santos, Fernando Pimentel
Gomes, Joao Lagoas
Aguiar, Renata
Videira, Taciana
Pinto, Patricia
Catita, Cristina
Santos, Helena
Borges, Joana
Sequeira, Graca
Ribeiro, Celia
Teixeira, Lidia
Avila-Ribeiro, Pedro
Martins, Fernando M.
Canhao, Helena
Ribeiro, Ruy M.
Fonseca, Joao Eurico
[J]. ANNALS OF THE RHEUMATIC DISEASES, 2019, 78 : 1266 - 1266
[2] GO-DACT: a phase 3b randomised, double-blind, placebo-controlled trial of GOlimumab plus methotrexate (MTX) versus placebo plus MTX in improving DACTylitis in MTX-naive patients with psoriatic arthritis
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Alves, Pedro
Rodrigues, Ana M.
Teixeira, Filipa
Tavares-Costa, Jose
Bernardo, Alexandra
Pimenta, Sofia
Pimentel-Santos, Fernando M.
Gomes, Joao Lagoas
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Pinto, Patricia
Videira, Taciana
Catita, Cristina
Santos, Helena
Borges, Joana
Sequeira, Graca
Ribeiro, Celia
Teixeira, Lidia
Avila-Ribeiro, Pedro
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Ribeiro, Ruy M.
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[3] THE GO-DACT PROTOCOL: A RANDOMIZED CONTROLLED TRIAL TO COMPARE THE EFFICACY OF GOLIMUMAB IN COMBINATION WITH METHOTREXATE (MTX) VERSUS MTX MONOTHERAPY, IN IMPROVING DACTYLITIS AND ENTHESITIS, IN MTX NAIVE PSORIATIC ARTHRITIS PATIENTS
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[4] THE GO-DACT PROTOCOL: A RANDOMIZED CONTROLLED TRIAL TO COMPARE THE EFFICACY OF GOLIMUMAB IN COMBINATION WITH METHOTREXATE (MTX) VERSUS MTX MONOTHERAPY, IN IMPROVING DACTYLITIS AND ENTHESITIS, IN MTX NAIVE PSORIATIC ARTHRITIS PATIENTS
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[5] THE GO-DACT PROTOCOL: A RANDOMISED CONTROLLED TRIAL TO COMPARE THE EFFICACY OF GOLIMUMAB IN COMBINATION WITH METHOTREXATE (MTX) VERSUS MTX MONOTHERAPY, IN IMPROVING DACTYLITIS AND ENTHESITIS, IN MTX NAIVE PSORIATIC ARTHRITIS PATIENTS
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[6] The GO-DACT protocol: a multicentre, randomized, double-blind, parallel-group study to compare the efficacy of golimumab in combination with methotrexate (MTX) versus MTX monotherapy, in improving dactylitis and enthesitis, in MTX-naive psoriatic arthritis patients
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[7] A PHASE 3, RANDOMIZED, DOUBLE-BLIND STUDY COMPARING UPADACITINIB MONOTHERAPY TO MTX MONOTHERAPY IN MTX-NAIVE PATIENTS WITH ACTIVE RHEUMATOID ARTHRITIS
van Vollenhoven, R.
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[J]. JCR-JOURNAL OF CLINICAL RHEUMATOLOGY, 2019, 25 : S4 - S4
[8] A 6 months double-blind randomized trial of methotrexate (MTX) plus chloroquine versus methotrexate plus placebo in rheumatoid arthritis (RA).
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[10] Achieving Remission in Psoriatic Arthritis By Early Initiation of TNF Inhibition: A Double-Blind, Randomized, Placebo-Controlled Trial of Golimumab plus Methotrexate Versus Placebo plus Methotrexate
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