Safety and efficacy of recombinant activated factor VIIa (rFVIIa) in traumatic intracerebral hemorrhage: Results of a prospective, randomized, multicenter dose-escalation clinical trial

被引:0
|
作者
Skolnick, Brett E.
Narayan, Raj K.
Marshall, Lawrence
Tillinger, Michael N.
Maas, Andrew
机构
关键词
D O I
10.1227/01.neu.0000279911.52806.f2
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
引用
收藏
页码:205 / 205
页数:1
相关论文
共 50 条
  • [1] Recombinant factor VIIA in traumatic intracerebral hemorrhage: Results of a dose-escalation clinical trial
    Narayan, Raj K.
    Maas, Andrew I. R.
    Marshall, Lawrence F.
    Servadei, Franco
    Skolnick, Brett E.
    Tillinger, Michael N.
    NEUROSURGERY, 2008, 62 (04) : 776 - 786
  • [2] Recombinant factor VIIA in traumatic intracerebral hemorrhage: Results of a dose-escalation clinical trial - Comments
    Marion, Donald W.
    Bullock, Ross M.
    Komotar, Ricardo J.
    Connolly, E. Sander, Jr.
    NEUROSURGERY, 2008, 62 (04) : 786 - 788
  • [3] Results of the CONTROL Trial: Efficacy and Safety of Recombinant Activated Factor VII in the Management of Refractory Traumatic Hemorrhage
    Hauser, Carl J.
    Boffard, Kenneth
    Dutton, Richard
    Bernard, Gordon R.
    Croce, Martin A.
    Holcomb, John B.
    Leppaniemi, Ari
    Parr, Michael
    Vincent, Jean-Louis
    Tortella, Bartholomew J.
    Dimsits, Jeannett
    Bouillon, Bertil
    JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE, 2010, 69 (03): : 489 - 500
  • [4] Efficacy and safety of recombinant activated factor VII for acute intracerebral hemorrhage
    Mayer, Stephan A.
    Brun, Nikolai C.
    Begtrup, Kamilla
    Broderick, Joseph
    Davis, Stephen
    Diringer, Michael N.
    Skolnick, Brett E.
    Steiner, Thorsten
    NEW ENGLAND JOURNAL OF MEDICINE, 2008, 358 (20): : 2127 - 2137
  • [5] Mesenchymal Stem Cell Therapy in Acute Intracerebral Hemorrhage: A Dose-Escalation Safety and Tolerability Trial
    Durand, Nisha C.
    Kim, H. G.
    Patel, Vishal N.
    Turnbull, Marion T.
    Siegel, Jason L.
    Hodge, David O.
    Tawk, Rabih G.
    Meschia, James F.
    Freeman, W. David
    Zubair, Abba C.
    NEUROCRITICAL CARE, 2024, 41 (01) : 59 - 69
  • [6] Design of a prospective, dose-escalation study evaluating the Safety of Pioglitazone for Hematoma Resolution in Intracerebral Hemorrhage (SHRINC)
    Gonzales, Nicole R.
    Shah, Jharna
    Sangha, Navdeep
    Sosa, Lenis
    Martinez, Rebecca
    Shen, Loren
    Kasam, Mallikarjunarao
    Morales, Miriam M.
    Hossain, M. Monir
    Barreto, Andrew D.
    Savitz, Sean I.
    Lopez, George
    Misra, Vivek
    Wu, Tzu-Ching
    El Khoury, Ramy
    Sarraj, Amrou
    Sahota, Preeti
    Hicks, William
    Acosta, Indrani
    Sline, M. Rick
    Rahbar, Mohammad H.
    Zhao, Xiurong
    Aronowski, Jaroslaw
    Grotta, James C.
    INTERNATIONAL JOURNAL OF STROKE, 2013, 8 (05) : 388 - 396
  • [7] Safety and preliminary efficacy of activated recombinant factor VII in acute intracerebral hemorrhage
    Mayer, S
    Brun, N
    STROKE, 2003, 34 (01) : 242 - 243
  • [8] A multicenter, randomized, double-blind, placebo-controlled, dose-escalation trial assessing safety and efficacy of active site inactivated recombinant factor VIIa in subjects with acute lung injury or acute respiratory distress syndrome
    Vincent, Jean-Louis
    Artigas, Antonio
    Petersen, Lars C.
    Meyer, Christian
    CRITICAL CARE MEDICINE, 2009, 37 (06) : 1874 - 1880
  • [9] SAFETY AND INITIAL CLINICAL EFFICACY OF 3 DOSE LEVELS OF RECOMBINANT ACTIVATED FACTOR-VII (RFVIIA) - RESULTS OF A PHASE-I STUDY
    MACIK, BG
    LINDLEY, CM
    LUSHER, J
    SAWYER, WT
    BLOOM, AL
    HARRISON, JF
    BAIRDCOX, K
    BIRCH, K
    GLAZER, S
    ROBERTS, HR
    BLOOD COAGULATION & FIBRINOLYSIS, 1993, 4 (04) : 521 - 527
  • [10] Randomized, prospective clinical trial of recombinant factor VIIa for secondary prophylaxis in hemophilia patients with inhibitors
    Konkle, B. A.
    Ebbesen, L. S.
    Erhardtsen, E.
    Bianco, R. P.
    Lissitchkov, T.
    Rusen, L.
    Serban, M. A.
    JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2007, 5 (09) : 1904 - 1913