NMR assignments for glucosylated and galactosylated N-acetylhexosaminitols:: oligosaccharide alditols related to O-linked glycans from the protozoan parasite Trypanosoma cruzi

被引：7
|
作者：
Jones, C
Previato, JO
Mendonça-Previato, L
机构：
[1] Natl Inst Biol Stand & Controls, Mol Struct Lab, S Mimms EN6 3QG, Herts, England
[2] Univ Fed Rio de Janeiro, Inst Microbiol, BR-21944970 Rio De Janeiro, Brazil
来源：
CARBOHYDRATE RESEARCH | 2000年 / 328卷 / 03期
关键词：
parasite mucins; O-glycans; N-acetylhexosaminitols; enzymatic synthesis; Trypanosoma cruzi;
D O I：
10.1016/S0008-6215(00)00107-5
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
We report full H-1 and C-13 NMR assignments for 13 gluco- or galacto-pyranosylated derivatives of GlcNAc-ol, GalNAc-ol or ManNAc-ol, many of which have been prepared by enzymatic methods. These spectra are reference data to aid the structural analysis by NMR spectroscopy of glycosylated alditols derived from the mucin of the protozoan parasite Trypanosoma cruzi. A series of structural reporter groups for the derivatives from this unusual series of O-glycans are described. (C) 2000 Elsevier Science Ltd. All rights reserved.
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收藏
页码：321 / 330
页数：10
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