Reversible Calcineurin Inhibitor-associated Sensorimotor Polyneuropathy in a Lung Transplant Recipient: A Case Report

被引：0

作者：

Antychin, T. ^{[1
,2
]}

Zarowski, J. A. ^{[1
,2
]}

Verplancke, V. ^{[1
,2
,3
]}

Hendriks, J. M. H. ^{[4
]}

Yogeswaran, S. K. ^{[4
]}

Lauwers, P. ^{[4
]}

Lamote, K. ^{[2
,3
,5
]}

Kwakkel-van Erp, J. M. ^{[1
,2
,3
,5
]}

机构：

[1] Univ Antwerp Hosp, Dept Pulmonol, Edegem, Belgium

[2] Univ Antwerp, Lab Expt Med & Pediat, Antwerp, Belgium

[3] Univ Antwerp, Infla Med Ctr Excellence, Antwerp, Belgium

[4] Univ Antwerp Hosp, Dept Thorac & Vasc Surg, Edegem, Belgium

[5] Univ Ghent, Dept Internal Med, Ghent, Belgium

来源：

INTERNATIONAL JOURNAL OF ORGAN TRANSPLANTATION MEDICINE | 2021年 / 12卷 / 04期

关键词：

Calcineurin inhibitors; mTOR-inhibitor; Lung transplantation; Reversible neuropathy; MTOR INHIBITORS; CYCLOSPORINE; TACROLIMUS;

D O I：

暂无

中图分类号：

R3 [基础医学]; R4 [临床医学];

学科分类号：

1001 ; 1002 ; 100602 ;

摘要：

YYYYY Calcineurin inhibitors (CNIs) are regarded as a corner stone in immunosuppressive therapy after solid organ transplantation. However, neurotoxicity is a common side effect of CNIs, resulting in a wide range of neurological symptoms such as headache, tremor and seizures. In this case report, we describe a patient who developed severe motor and sensory neuron dysfunction related to CNIs after bilateral lung transplantation, which resolved after halting CNI and switching to a mammalian Target of Rapamycin-inhibitor.

引用

页码：60 / 64

页数：5

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