Polymer carriers for drug delivery in tissue engineering

被引：313
|
作者：
Sokolsky-Papkov, Marina
Agashi, Kapil
Olaye, Andrew
Shakesheff, Kevin
Domb, Abraham J. [1 ]
机构：
[1] Hebrew Univ Jerusalem, Fac Med, Sch Pharm, Dept Med Chem & Nat Prod, IL-91120 Jerusalem, Israel
[2] Univ Nottingham, Sch Pharm, STEM, Div Drug Delivery & Tissue Engn,CBS, Nottingham NG7 2RD, England
来源：
ADVANCED DRUG DELIVERY REVIEWS | 2007年 / 59卷 / 4-5期
关键词：
scaffold; scaffold fabrication; polyester; collagen blends;
D O I：
10.1016/j.addr.2007.04.001
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Growing demand for tissues and organs for transplantation and the inability to meet this need using by autogeneic (from the host) or allogeneic (from the same species) sources has led to the rapid development of tissue engineering as an alternative. Tissue engineering aims to replace or facilitate the regrowth of damaged or diseased tissue by applying a combination of biomaterials, cells and bioactive molecules. This review focuses on synthetic polymers that have been used for tissue growth scaffold fabrication and their applications in both cell and extracellular matrix support and controlling the release of cell growth and differentiation supporting drugs. (c) 2007 Elsevier B.V. All rights reserved.
引用
收藏
页码：187 / 206
页数：20
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