SARS-CoV-2 Rapid Antigen Testing of Symptomatic and Asymptomatic Individuals on the University of Arizona Campus

被引：12

作者：

Harris, David T. ^{[1
,2
]}

Badowski, Michael ^{[1
]}

Jernigan, Brandon ^{[1
]}

Sprissler, Ryan ^{[3
]}

Edwards, Taylor ^{[3
]}

Cohen, Randall ^{[4
]}

Paul, Stephen ^{[4
]}

Merchant, Nirav ^{[5
]}

Weinkauf, Craig C. ^{[6
]}

Bime, Christian ^{[7
]}

Erickson, Heidi E. ^{[7
]}

Bixby, Billie ^{[7
]}

Parthasarathy, Sairam ^{[7
]}

Chaudhary, Sachin ^{[7
]}

Natt, Bhupinder ^{[7
]}

Cristan, Elaine ^{[7
]}

El Aini, Tammer ^{[7
]}

Rischard, Franz ^{[7
]}

Campion, Janet ^{[7
]}

Chopra, Madhav ^{[7
]}

Insel, Michael ^{[7
]}

Sam, Afshin ^{[7
]}

Knepler, James L. ^{[7
]}

Knox, Kenneth ^{[8
]}

Mosier, Jarrod ^{[9
]}

Spier, Catherine ^{[10
]}

Dake, Michael D. ^{[11
]}

机构：

[1] Univ Arizona, Biorepository, Coll Med Tucson, Univ Arizona Hlth Sci, Tucson, AZ 85724 USA

[2] Univ Arizona, Dept Immunobiol & Med, Coll Med Tucson, Univ Arizona Hlth Sci, Tucson, AZ 85724 USA

[3] Univ Arizona, Univ Arizona Genet Core, Coll Med Tucson, Tucson, AZ 85724 USA

[4] Univ Arizona, Dept Athlet, Tucson, AZ 85724 USA

[5] Univ Arizona, Data Sci Inst, Tucson, AZ 85724 USA

[6] Univ Arizona, Dept Surg, Coll Med Tucson, Tucson, AZ 85724 USA

[7] Univ Arizona, Div Pulm Allergy Crit Care & Sleep Med, Coll Med Tucson, Tucson, AZ 85724 USA

[8] Univ Arizona, Dept Med, Tucson, AZ 85724 USA

[9] Coll Med Tucson, Dept Emergency Med, Tucson, AZ 85724 USA

[10] Univ Arizona, Dept Pathol, Coll Med Tucson, Tucson, AZ 85724 USA

[11] Univ Arizona, Off Senior Vice President Hlth Sci, Tucson, AZ 85724 USA

来源：

BIOMEDICINES | 2021年 / 9卷 / 05期

关键词：

rapid antigen test; PCR; SARS-CoV-2; asymptomatic; diagnostic screening; PCR;

D O I：

10.3390/biomedicines9050539

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

SARS-CoV-2, the cause of COVID19, has caused a pandemic that has infected more than 80 M and killed more than 1.6 M persons worldwide. In the US as of December 2020, it has infected more than 32 M people while causing more than 570,000 deaths. As the pandemic persists, there has been a public demand to reopen schools and university campuses. To consider these demands, it is necessary to rapidly identify those individuals infected with the virus and isolate them so that disease transmission can be stopped. In the present study, we examined the sensitivity of the Quidel Rapid Antigen test for use in screening both symptomatic and asymptomatic individuals at the University of Arizona from June to August 2020. A total of 885 symptomatic and 1551 asymptomatic subjects were assessed by antigen testing and real-time PCR testing. The sensitivity of the test for both symptomatic and asymptomatic persons was between 82 and 90%, with some caveats.

引用

页数：9

共 50 条

[1] A comparison of SARS-CoV-2 rapid antigen testing with realtime RT-PCR among symptomatic and asymptomatic individuals
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[J]. BMC Infectious Diseases, 23
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[J]. BMC INFECTIOUS DISEASES, 2023, 23 (01)
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