On comparing in vivo intracranial recordings in non-human primates to predictions of optimized transcranial electrical stimulation

被引:0
|
作者
Datta, Abhishek [1 ]
Krause, Matthew R. [2 ]
Pilly, Praveen K. [3 ]
Choe, Jaehoon [3 ]
Zanos, Theodoros P. [2 ]
Thomas, Chris [1 ]
Pack, Christopher C. [2 ]
机构
[1] Soterix Med Inc, Res & Dev, New York, NY 10001 USA
[2] McGill Univ, Montreal Neurol Inst, Montreal, PQ H3A 2B4, Canada
[3] HRL Labs LLC, Informat & Syst Sci Lab, Malibu, CA 90265 USA
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中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Transcranial electrical stimulation (tES) can be optimized to achieve maximal current flow at desired brain regions. The aim of this study was to characterize electric field magnitudes generated by tES optimization and to compare them to experimentally induced values as determined by data from intracranial electrodes. Local field potentials were recorded from two monkeys with implanted multi-site intracranial Utah arrays during transcranial direct current stimulation (tDCS), and the neural effect predictions obtained from optimized electrode placement were assessed. Comparative data between the two sites of intracranial recordings during tDCS partially validated the predictions of our tES optimization algorithms.
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页码:1774 / 1777
页数:4
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