Recognition of Risk for Clinically Significant Drug Interactions among HIV-Infected Patients Receiving Antiretroviral Therapy

被引：63

作者：

Evans-Jones, John G. ^{[2
]}

Cottle, Lucy E. ^{[3
]}

Back, David J. ^{[1
]}

Gibbons, Sara ^{[1
]}

Beeching, Nicholas J. ^{[3
]}

Carey, Peter B. ^{[2
]}

Khoo, Saye H. ^{[1
,2
]}

机构：

[1] Univ Liverpool, Sch Biomed Sci, Dept Pharmacol, Liverpool L69 3GE, Merseyside, England

[2] Royal Liverpool & Broadgreen Univ Hosp NHS Trust, Dept Genitourinary Med, Liverpool, Merseyside, England

[3] Royal Liverpool & Broadgreen Univ Hosp NHS Trust, Dept Infect Dis, Liverpool, Merseyside, England

来源：

CLINICAL INFECTIOUS DISEASES | 2010年 / 50卷 / 10期

基金：

英国医学研究理事会;

关键词：

D O I：

10.1086/652149

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We assessed the risk of clinically significant drug interactions in patients receiving antiretrovirals, and their recognition by physicians. Clinically significant drug interactions were recorded in 27% of 159 patients, with 15% of interactions potentially lowering antiretroviral concentrations. Risk of clinically significant drug interactions was significantly related to receipt of protease inhibitors. Only 36% of clinically significant drug interactions were correctly identified by physicians.

引用

页码：1419 / 1421

页数：3

共 50 条

[1] CLINICALLY SIGNIFICANT DRUG INTERACTIONS AMONG HIV-INFECTED PATIENTS RECEIVING ANTIRETROVIRAL THERAPY
So-Ngern, Apichot
Montakantikul, Preecha
Manosuthi, Weerawat
[J]. SOUTHEAST ASIAN JOURNAL OF TROPICAL MEDICINE AND PUBLIC HEALTH, 2014, 45 (05) : 1023 - 1031
[2] Clinically significant drug interactions among HIV-infected patients receiving antiretroviral therapy in outpatient HIV clinic
So-Ngern, A.
Manosuthi, W.
[J]. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 2013, 42 : S72 - S72
[3] Risk of clinically significant depression in HIV-infected patients: effect of antiretroviral drugs
Gutierrez, F.
Garcia, L.
Padilla, S.
Alvarez, D.
Moreno, S.
Navarro, G.
Gomez-Sirvent, J. L.
Vidal, F.
Asensi, V.
Masia, M.
[J]. HIV MEDICINE, 2014, 15 (04) : 213 - 223
[4] Gynecomastia in HIV-infected patients receiving antiretroviral therapy
García-Benayas, T
Blanco, F
Martín-Carbonero, L
Valencia, E
Barrios, A
González-Lahoz, J
Soriano, V
[J]. AIDS RESEARCH AND HUMAN RETROVIRUSES, 2003, 19 (09) : 739 - 741
[5] Polypharmacy and Risk of Antiretroviral Drug Interactions Among the Aging HIV-Infected Population
Carol Holtzman
Carl Armon
Ellen Tedaldi
Joan S. Chmiel
Kate Buchacz
Kathleen Wood
John T. Brooks
[J]. Journal of General Internal Medicine, 2013, 28 : 1302 - 1310
[6] Polypharmacy and Risk of Antiretroviral Drug Interactions Among the Aging HIV-Infected Population
Holtzman, Carol
Armon, Carl
Tedaldi, Ellen
Chmiel, Joan S.
Buchacz, Kate
Wood, Kathleen
Brooks, John T.
[J]. JOURNAL OF GENERAL INTERNAL MEDICINE, 2013, 28 (10) : 1302 - 1310
[7] IMPACT OF TUBERCULOSIS ON MORTALITY AMONG HIV-INFECTED PATIENTS RECEIVING ANTIRETROVIRAL THERAPY
Chu, R.
Mills, E.
Beyene, J.
Bakanda, C.
Nachega, J.
Thabane, L.
[J]. AMERICAN JOURNAL OF EPIDEMIOLOGY, 2011, 173 : S73 - S73
[8] Risk factors for tuberculosis among HIV-infected patients receiving antiretroviral treatment
Lawn, SD
Badri, M
Wood, R
[J]. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2005, 172 (10) : 1348 - 1348
[9] Retention in Care Among HIV-infected Patients Receiving or Not Receiving Antiretroviral Therapy in Eastern Africa
Reidy, William
Agarwal, Mansi
Chege, Duncan
Lamb, Matthew
Hawken, Mark
Mukui, Irene
Abrams, Elaine
Geng, Elvin
[J]. CLINICAL INFECTIOUS DISEASES, 2016, 63 (03) : 426 - +
[10] Causes of Death and Risk Factors for Mortality among HIV-Infected Patients Receiving Antiretroviral Therapy in Korea
Lee, Sun Hee
Kim, Kye-Hyung
Lee, Seung Geun
Cho, Heerim
Chen, Dong Hwan
Chung, Joo Seop
Kwak, Ihm Soo
Cho, Goon Jae
[J]. JOURNAL OF KOREAN MEDICAL SCIENCE, 2013, 28 (07) : 990 - 997

← 1 2 3 4 5 →