Prevention of radioinduced LDL peroxidation by vitamin E derivatives

被引：3
|
作者：
Clavere, P
Jore, D
GardesAlbert, M
Lepage, S
BonnefontRousselot, D
Delattre, J
机构：
[1] UNIV PARIS 05,URA 400 CNRS,CHIM PHYS LAB,F-75720 PARIS 06,FRANCE
[2] HOP UNIV DUPUYTREN,SERV RADIOTHERAPIE & CARCINOL,F-87042 LIMOGES,FRANCE
[3] HOP LA PITIE SALPETRIERE,BIOCHIM LAB,F-75651 PARIS 13,FRANCE
来源：
JOURNAL DE CHIMIE PHYSIQUE ET DE PHYSICO-CHIMIE BIOLOGIQUE | 1996年 / 93卷 / 01期
关键词：
vitamin E derivatives; LDL; steady state radiolysis; free radicals; peroxidation;
D O I：
10.1051/jcp/1996930053
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The prevention of human LDL peroxidation by a vitamin E derivative has been studied by steady state radiolysis. The consequences of the action of increasing radiation doses have been monitored by several parameters : the formation of thiobarbituric acid reactive substances (TBARS), the decrease in endogenous vitamin E and the decrease of vitamin E analog. The obtained results indicate the protective effect of the vitamin E analog against the peroxidation initiated by OHo/O2(o-) free radicals in the presence of oxygen.
引用
收藏
页码：53 / 57
页数：5
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