Serum Vitamin D Level and the Risk of Urinary Tract Infection in Children: A Systematic Review and Meta-Analysis

被引：6
|
作者：
Li, Xiaoyan [1 ]
Yu, Qing [1 ]
Qin, Feng [1 ]
Zhang, Biyu [1 ]
Lu, Yanming [1 ]
机构：
[1] Shanghai Jiao Tong Univ, Renji Hosp, Dept Pediat, Sch Med, Shanghai, Peoples R China
来源：
FRONTIERS IN PUBLIC HEALTH | 2021年 / 9卷
关键词：
urinary tract infection; vitamin D; children; meta-analysis; UTI; ESCHERICHIA-COLI; ASSOCIATION;
D O I：
10.3389/fpubh.2021.637529
中图分类号：
R1 [预防医学、卫生学];
学科分类号：
1004 ; 120402 ;
摘要：
This systematic review and meta-analysis aimed to evaluate the association between serum vitamin D concentration and the risk of urinary tract infection (UTI) in children. Human studies reported the serum vitamin D level in children with UTI and healthy controls were collected from PubMed, Scopus, Embase, and Cochrane databases. The strictly standardized mean difference (SSMD) and 95% confidence interval (CI) were calculated to evaluate the relationship between serum vitamin D levels and risk of UTI. The results of analysis showed that serum vitamin D levels in children with UTI were significantly lower than healthy control children (SSMD: 0.891, 95% CI: 0.707-1.075, p < 0.000; SSMD: 0.797, 95% CI: 0.500-1.094, p < 0.000, respectively). It can be concluded that there is a significant negative relationship between serum vitamin D level and risk of UTI in children.
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页数：7
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