The human Pol III transcriptome and gene information flow

被引：7
|
作者：
Noma, Ken-ichi [1 ]
Kamakaka, Rohinton T. [2 ]
机构：
[1] Wistar Inst Anat & Biol, Philadelphia, PA USA
[2] Univ Calif Santa Cruz, Dept Mol Cell & Dev Biol, Santa Cruz, CA 95064 USA
来源：
NATURE STRUCTURAL & MOLECULAR BIOLOGY | 2010年 / 17卷 / 05期
关键词：
RNA-POLYMERASE-II; SACCHAROMYCES-CEREVISIAE; FISSION YEAST; LOCALIZATION; ACTIVATION; MACHINERY; DOMAIN;
D O I：
10.1038/nsmb0510-539
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
In this issue, three papers report the distribution of the RNA polymerase III (Pol III) machinery, including transcription factor IIIB, transcription factor IIIC and Pol III itself, across the human genome. These studies reveal cell type–specific expression of Pol III genes, functional interplay between the Pol II and Pol III transcriptional machineries and the potential involvement of Pol III genes in chromosome organization.
引用
收藏
页码：539 / 541
页数：3
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