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- [1] Lentiviral Insertional Mutagenesis Helps to Uncover the Mechanisms of Resistance to AZD9291 and CO-1686 in EGFR-Mutant Lung Adenocarcinoma[J]. MOLECULAR THERAPY, 2016, 24 : S83 - S83Pirazzoli, Valentina论文数: 0 引用数: 0 h-index: 0机构: HSR TIGET, Milan, Italy HSR TIGET, Milan, ItalySpinozzi, Giulio论文数: 0 引用数: 0 h-index: 0机构: HSR TIGET, Milan, Italy HSR TIGET, Milan, ItalyTenderini, Erika论文数: 0 引用数: 0 h-index: 0机构: HSR TIGET, Milan, Italy HSR TIGET, Milan, ItalyBenedicenti, Fabrizio论文数: 0 引用数: 0 h-index: 0机构: HSR TIGET, Milan, Italy HSR TIGET, Milan, ItalyCalabria, Andrea论文数: 0 引用数: 0 h-index: 0机构: HSR TIGET, Milan, Italy HSR TIGET, Milan, ItalyMontini, Eugenio论文数: 0 引用数: 0 h-index: 0机构: HSR TIGET, Milan, Italy HSR TIGET, Milan, Italy
- [2] The third-generation EGFR inhibitor AZD9291 overcomes primary resistance by continuously blocking ERK signaling in glioblastoma[J]. Journal of Experimental & Clinical Cancer Research, 38Xuejiao Liu论文数: 0 引用数: 0 h-index: 0机构: Affiliated Hospital of Xuzhou Medical University,Insititute of Nervous System DiseasesXiangyu Chen论文数: 0 引用数: 0 h-index: 0机构: Affiliated Hospital of Xuzhou Medical University,Insititute of Nervous System DiseasesLin Shi论文数: 0 引用数: 0 h-index: 0机构: Affiliated Hospital of Xuzhou Medical University,Insititute of Nervous System DiseasesQianqian Shan论文数: 0 引用数: 0 h-index: 0机构: Affiliated Hospital of Xuzhou Medical University,Insititute of Nervous System DiseasesQiyu Cao论文数: 0 引用数: 0 h-index: 0机构: Affiliated Hospital of Xuzhou Medical University,Insititute of Nervous System DiseasesChenglong Yue论文数: 0 引用数: 0 h-index: 0机构: Affiliated Hospital of Xuzhou Medical University,Insititute of Nervous System DiseasesHuan Li论文数: 0 引用数: 0 h-index: 0机构: Affiliated Hospital of Xuzhou Medical University,Insititute of Nervous System DiseasesShengsheng Li论文数: 0 引用数: 0 h-index: 0机构: Affiliated Hospital of Xuzhou Medical University,Insititute of Nervous System DiseasesJie Wang论文数: 0 引用数: 0 h-index: 0机构: Affiliated Hospital of Xuzhou Medical University,Insititute of Nervous System DiseasesShangfeng Gao论文数: 0 引用数: 0 h-index: 0机构: Affiliated Hospital of Xuzhou Medical University,Insititute of Nervous System DiseasesMingshan Niu论文数: 0 引用数: 0 h-index: 0机构: Affiliated Hospital of Xuzhou Medical University,Insititute of Nervous System DiseasesRutong Yu论文数: 0 引用数: 0 h-index: 0机构: Affiliated Hospital of Xuzhou Medical University,Insititute of Nervous System Diseases
- [3] The third-generation EGFR inhibitor AZD9291 overcomes primary resistance by continuously blocking ERK signaling in glioblastoma[J]. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2019, 38 (1)Liu, Xuejiao论文数: 0 引用数: 0 h-index: 0机构: Xuzhou Med Univ, Affiliated Hosp, Inst Nervous Syst Dis, Xuzhou, Jiangsu, Peoples R China Xuzhou Med Univ, Affiliated Hosp, Dept Neurosurg, Xuzhou, Jiangsu, Peoples R China Xuzhou Med Univ, Affiliated Hosp, Inst Nervous Syst Dis, Xuzhou, Jiangsu, Peoples R ChinaChen, Xiangyu论文数: 0 引用数: 0 h-index: 0机构: Xuzhou Med Univ, Affiliated Hosp, Inst Nervous Syst Dis, Xuzhou, Jiangsu, Peoples R China Xuzhou Med Univ, Affiliated Hosp, Dept Neurosurg, Xuzhou, Jiangsu, Peoples R China Xuzhou Med Univ, Affiliated Hosp, Inst Nervous Syst Dis, Xuzhou, Jiangsu, Peoples R ChinaShi, Lin论文数: 0 引用数: 0 h-index: 0机构: Xuzhou Med Univ, Affiliated Hosp, Inst Nervous Syst Dis, Xuzhou, Jiangsu, Peoples R China Xuzhou Med Univ, Affiliated Hosp, Dept Neurosurg, Xuzhou, Jiangsu, Peoples R China Xuzhou Med Univ, Affiliated Hosp, Inst Nervous Syst Dis, Xuzhou, Jiangsu, Peoples R ChinaShan, Qianqian论文数: 0 引用数: 0 h-index: 0机构: Xuzhou Med Univ, Affiliated Hosp, Inst Nervous Syst Dis, Xuzhou, Jiangsu, Peoples R China Xuzhou Med Univ, Affiliated Hosp, Inst Nervous Syst Dis, Xuzhou, Jiangsu, Peoples R ChinaCao, Qiyu论文数: 0 引用数: 0 h-index: 0机构: Xuzhou Med Univ, Affiliated Hosp, Inst Nervous Syst Dis, Xuzhou, Jiangsu, Peoples R China Xuzhou Med Univ, Affiliated Hosp, Inst Nervous Syst Dis, Xuzhou, Jiangsu, Peoples R ChinaYue, Chenglong论文数: 0 引用数: 0 h-index: 0机构: Xuzhou Childrens Hosp, Surg Dept 9, Xuzhou, Jiangsu, Peoples R China Xuzhou Med Univ, Affiliated Hosp, Inst Nervous Syst Dis, Xuzhou, Jiangsu, Peoples R ChinaLi, Huan论文数: 0 引用数: 0 h-index: 0机构: Xuzhou Med Univ, Affiliated Hosp, Inst Nervous Syst Dis, Xuzhou, Jiangsu, Peoples R China Xuzhou Med Univ, Affiliated Hosp, Inst Nervous Syst Dis, Xuzhou, Jiangsu, Peoples R ChinaLi, Shengsheng论文数: 0 引用数: 0 h-index: 0机构: Xuzhou Med Univ, Affiliated Hosp, Inst Nervous Syst Dis, Xuzhou, Jiangsu, Peoples R China Xuzhou Med Univ, Affiliated Hosp, Inst Nervous Syst Dis, Xuzhou, Jiangsu, Peoples R ChinaWang, Jie论文数: 0 引用数: 0 h-index: 0机构: Xuzhou Med Univ, Affiliated Hosp, Inst Nervous Syst Dis, Xuzhou, Jiangsu, Peoples R China Xuzhou Med Univ, Affiliated Hosp, Inst Nervous Syst Dis, Xuzhou, Jiangsu, Peoples R ChinaGao, Shangfeng论文数: 0 引用数: 0 h-index: 0机构: Xuzhou Med Univ, Affiliated Hosp, Inst Nervous Syst Dis, Xuzhou, Jiangsu, Peoples R China Xuzhou Med Univ, Affiliated Hosp, Dept Neurosurg, Xuzhou, Jiangsu, Peoples R China Xuzhou Med Univ, Affiliated Hosp, Inst Nervous Syst Dis, Xuzhou, Jiangsu, Peoples R ChinaNiu, Mingshan论文数: 0 引用数: 0 h-index: 0机构: Xuzhou Med Univ, Affiliated Hosp, Inst Nervous Syst Dis, Xuzhou, Jiangsu, Peoples R China Xuzhou Med Univ, Blood Dis Inst, Xuzhou, Jiangsu, Peoples R China Xuzhou Med Univ, Affiliated Hosp, Inst Nervous Syst Dis, Xuzhou, Jiangsu, Peoples R ChinaYu, Rutong论文数: 0 引用数: 0 h-index: 0机构: Xuzhou Med Univ, Affiliated Hosp, Inst Nervous Syst Dis, Xuzhou, Jiangsu, Peoples R China Xuzhou Med Univ, Affiliated Hosp, Dept Neurosurg, Xuzhou, Jiangsu, Peoples R China Xuzhou Med Univ, Affiliated Hosp, Inst Nervous Syst Dis, Xuzhou, Jiangsu, Peoples R China
- [4] AZD9291, an Irreversible EGFR TKI, Overcomes T790M-Mediated Resistance to EGFR Inhibitors in Lung Cancer[J]. CANCER DISCOVERY, 2014, 4 (09) : 1046 - 1061Cross, Darren A. E.论文数: 0 引用数: 0 h-index: 0机构: AstraZeneca, Oncol Innovat Med, Macclesfield SK10 4TG, Cheshire, England AstraZeneca, Oncol Innovat Med, Macclesfield SK10 4TG, Cheshire, EnglandAshton, Susan E.论文数: 0 引用数: 0 h-index: 0机构: AstraZeneca, Oncol Innovat Med, Macclesfield SK10 4TG, Cheshire, England AstraZeneca, Oncol Innovat Med, Macclesfield SK10 4TG, Cheshire, EnglandGhiorghiu, Serban论文数: 0 引用数: 0 h-index: 0机构: AstraZeneca, Oncol Innovat Med, Macclesfield SK10 4TG, Cheshire, England AstraZeneca, Oncol Innovat Med, Macclesfield SK10 4TG, Cheshire, EnglandEberlein, Cath论文数: 0 引用数: 0 h-index: 0机构: AstraZeneca, Oncol Innovat Med, Macclesfield SK10 4TG, Cheshire, England AstraZeneca, Oncol Innovat Med, Macclesfield SK10 4TG, Cheshire, EnglandNebhan, Caroline A.论文数: 0 引用数: 0 h-index: 0机构: Vanderbilt Univ, Dept Med, Nashville, TN USA Vanderbilt Univ, Vanderbilt Ingram Canc Ctr, Nashville, TN 37235 USA AstraZeneca, Oncol Innovat Med, Macclesfield SK10 4TG, Cheshire, EnglandSpitzler, Paula J.论文数: 0 引用数: 0 h-index: 0机构: Vanderbilt Univ, Dept Med, Nashville, TN USA Vanderbilt Univ, Vanderbilt Ingram Canc Ctr, Nashville, TN 37235 USA AstraZeneca, Oncol Innovat Med, Macclesfield SK10 4TG, Cheshire, EnglandOrme, Jonathon P.论文数: 0 引用数: 0 h-index: 0机构: AstraZeneca, Discovery Sci, Macclesfield SK10 4TG, Cheshire, England AstraZeneca, Oncol Innovat Med, Macclesfield SK10 4TG, Cheshire, EnglandFinlay, M. Raymond V.论文数: 0 引用数: 0 h-index: 0机构: AstraZeneca, Oncol Innovat Med, Macclesfield SK10 4TG, Cheshire, England AstraZeneca, Oncol Innovat Med, Macclesfield SK10 4TG, Cheshire, EnglandWard, Richard A.论文数: 0 引用数: 0 h-index: 0机构: AstraZeneca, Oncol Innovat Med, Macclesfield SK10 4TG, Cheshire, England AstraZeneca, Oncol Innovat Med, Macclesfield SK10 4TG, Cheshire, EnglandMellor, Martine J.论文数: 0 引用数: 0 h-index: 0机构: AstraZeneca, Oncol Innovat Med, Macclesfield SK10 4TG, Cheshire, England AstraZeneca, Oncol Innovat Med, Macclesfield SK10 4TG, Cheshire, EnglandHughes, Gareth论文数: 0 引用数: 0 h-index: 0机构: AstraZeneca, Oncol Innovat Med, Macclesfield SK10 4TG, Cheshire, England AstraZeneca, Oncol Innovat Med, Macclesfield SK10 4TG, Cheshire, EnglandRahi, Amar论文数: 0 引用数: 0 h-index: 0机构: AstraZeneca, Oncol Innovat Med, Macclesfield SK10 4TG, Cheshire, England AstraZeneca, Oncol Innovat Med, Macclesfield SK10 4TG, Cheshire, EnglandJacobs, Vivien N.论文数: 0 引用数: 0 h-index: 0机构: AstraZeneca, Oncol Innovat Med, Macclesfield SK10 4TG, Cheshire, England AstraZeneca, Oncol Innovat Med, Macclesfield SK10 4TG, Cheshire, EnglandBrewer, Monica Red论文数: 0 引用数: 0 h-index: 0机构: Vanderbilt Univ, Dept Med, Nashville, TN USA Vanderbilt Univ, Vanderbilt Ingram Canc Ctr, Nashville, TN 37235 USA AstraZeneca, Oncol Innovat Med, Macclesfield SK10 4TG, Cheshire, EnglandIchihara, Eiki论文数: 0 引用数: 0 h-index: 0机构: Vanderbilt Univ, Dept Med, Nashville, TN USA Vanderbilt Univ, Vanderbilt Ingram Canc Ctr, Nashville, TN 37235 USA AstraZeneca, Oncol Innovat Med, Macclesfield SK10 4TG, Cheshire, EnglandSun, Jing论文数: 0 引用数: 0 h-index: 0机构: Vanderbilt Univ, Dept Med, Nashville, TN USA Vanderbilt Univ, Vanderbilt Ingram Canc Ctr, Nashville, TN 37235 USA AstraZeneca, Oncol Innovat Med, Macclesfield SK10 4TG, Cheshire, EnglandJin, Hailing论文数: 0 引用数: 0 h-index: 0机构: Vanderbilt Univ, Dept Med, Nashville, TN USA Vanderbilt Univ, Vanderbilt Ingram Canc Ctr, Nashville, TN 37235 USA AstraZeneca, Oncol Innovat Med, Macclesfield SK10 4TG, Cheshire, EnglandBallard, Peter论文数: 0 引用数: 0 h-index: 0机构: AstraZeneca, Oncol Innovat Med, Macclesfield SK10 4TG, Cheshire, England AstraZeneca, Oncol Innovat Med, Macclesfield SK10 4TG, Cheshire, EnglandAl-Kadhimi, Katherine论文数: 0 引用数: 0 h-index: 0机构: AstraZeneca, Oncol Innovat Med, Macclesfield SK10 4TG, Cheshire, England AstraZeneca, Oncol Innovat Med, Macclesfield SK10 4TG, Cheshire, EnglandRowlinson, Rachel论文数: 0 引用数: 0 h-index: 0机构: AstraZeneca, Oncol Innovat Med, Macclesfield SK10 4TG, Cheshire, England AstraZeneca, Oncol Innovat Med, Macclesfield SK10 4TG, Cheshire, EnglandKlinowska, Teresa论文数: 0 引用数: 0 h-index: 0机构: AstraZeneca, Oncol Innovat Med, Macclesfield SK10 4TG, Cheshire, England AstraZeneca, Oncol Innovat Med, Macclesfield SK10 4TG, Cheshire, EnglandRichmond, Graham H. P.论文数: 0 引用数: 0 h-index: 0机构: AstraZeneca, Oncol Innovat Med, Macclesfield SK10 4TG, Cheshire, England AstraZeneca, Oncol Innovat Med, Macclesfield SK10 4TG, Cheshire, EnglandCantarini, Mireille论文数: 0 引用数: 0 h-index: 0机构: AstraZeneca, Oncol Innovat Med, Macclesfield SK10 4TG, Cheshire, England AstraZeneca, Oncol Innovat Med, Macclesfield SK10 4TG, Cheshire, EnglandKim, Dong-Wan论文数: 0 引用数: 0 h-index: 0机构: Seoul Natl Univ Hosp, Seoul 110744, South Korea AstraZeneca, Oncol Innovat Med, Macclesfield SK10 4TG, Cheshire, EnglandRanson, Malcolm R.论文数: 0 引用数: 0 h-index: 0机构: Univ Manchester, Christie Hosp, Manchester, Lancs, England AstraZeneca, Oncol Innovat Med, Macclesfield SK10 4TG, Cheshire, EnglandPao, William论文数: 0 引用数: 0 h-index: 0机构: Vanderbilt Univ, Dept Med, Nashville, TN USA Vanderbilt Univ, Vanderbilt Ingram Canc Ctr, Nashville, TN 37235 USA AstraZeneca, Oncol Innovat Med, Macclesfield SK10 4TG, Cheshire, England
- [5] ERK pathway activation is associated with acquired resistance to AZD9291, a third-generation irreversible inhibitor targeting EGFR sensitizing (EGFRm plus ) and resistance (T790M) mutations in NSCLC[J]. CLINICAL CANCER RESEARCH, 2015, 21Eberlein, Cath论文数: 0 引用数: 0 h-index: 0机构: AstraZeneca, Macclesfield, Cheshire, England AstraZeneca, Macclesfield, Cheshire, EnglandAl-Kadhimi, Katie论文数: 0 引用数: 0 h-index: 0机构: AstraZeneca, Macclesfield, Cheshire, England AstraZeneca, Macclesfield, Cheshire, EnglandRoss, Sarah论文数: 0 引用数: 0 h-index: 0机构: AstraZeneca, Macclesfield, Cheshire, England AstraZeneca, Macclesfield, Cheshire, EnglandBrown, Henry论文数: 0 引用数: 0 h-index: 0机构: AstraZeneca, Macclesfield, Cheshire, England AstraZeneca, Macclesfield, Cheshire, EnglandFisher, Paul论文数: 0 引用数: 0 h-index: 0机构: AstraZeneca, Macclesfield, Cheshire, England AstraZeneca, Macclesfield, Cheshire, EnglandStetson, Daniel论文数: 0 引用数: 0 h-index: 0机构: AstraZeneca, Boston, MA USA AstraZeneca, Macclesfield, Cheshire, EnglandLai, Zhongwu论文数: 0 引用数: 0 h-index: 0机构: AstraZeneca, Boston, MA USA AstraZeneca, Macclesfield, Cheshire, EnglandThress, Kenneth论文数: 0 引用数: 0 h-index: 0机构: AstraZeneca, Boston, MA USA AstraZeneca, Macclesfield, Cheshire, EnglandDougherty, Brian论文数: 0 引用数: 0 h-index: 0机构: AstraZeneca, Boston, MA USA AstraZeneca, Macclesfield, Cheshire, EnglandPao, William论文数: 0 引用数: 0 h-index: 0机构: Vanderbilt Univ, Nashville, TN 37235 USA AstraZeneca, Macclesfield, Cheshire, EnglandCross, Darren论文数: 0 引用数: 0 h-index: 0机构: AstraZeneca, Macclesfield, Cheshire, England AstraZeneca, Macclesfield, Cheshire, England
- [6] Preclinical comparison of the blood brain barrier (BBB) permeability of osimertinib (AZD9291) with other irreversible next generation EGFR TKIs[J]. EUROPEAN JOURNAL OF CANCER, 2016, 69 : S28 - S28Colclough, N.论文数: 0 引用数: 0 h-index: 0机构: AstraZeneca, Oncol IMED, Macclesfield, Cheshire, England AstraZeneca, Oncol IMED, Macclesfield, Cheshire, EnglandBallard, P. G.论文数: 0 引用数: 0 h-index: 0机构: AstraZeneca, Oncol IMED, Macclesfield, Cheshire, England AstraZeneca, Oncol IMED, Macclesfield, Cheshire, EnglandBarton, P.论文数: 0 引用数: 0 h-index: 0机构: AstraZeneca, Oncol IMED, Cambridge, England AstraZeneca, Oncol IMED, Macclesfield, Cheshire, EnglandChen, K.论文数: 0 引用数: 0 h-index: 0机构: AstraZeneca, Asia & Emerging Markets IMED, Shanghai, Peoples R China AstraZeneca, Oncol IMED, Macclesfield, Cheshire, EnglandCross, D. A. E.论文数: 0 引用数: 0 h-index: 0机构: AstraZeneca, Oncol IMED, Cambridge, England AstraZeneca, Oncol IMED, Macclesfield, Cheshire, EnglandFinlay, M. R. V.论文数: 0 引用数: 0 h-index: 0机构: AstraZeneca, Oncol IMED, Cambridge, England AstraZeneca, Oncol IMED, Macclesfield, Cheshire, EnglandHan, L.论文数: 0 引用数: 0 h-index: 0机构: AstraZeneca, Asia & Emerging Markets IMED, Shanghai, Peoples R China AstraZeneca, Oncol IMED, Macclesfield, Cheshire, EnglandJanefeldt, A.论文数: 0 引用数: 0 h-index: 0机构: AstraZeneca, CVMD IMED, Gothenburg, Sweden AstraZeneca, Oncol IMED, Macclesfield, Cheshire, EnglandJohnstrom, P.论文数: 0 引用数: 0 h-index: 0机构: Karolinska Inst, AstraZeneca, Translat Sci Ctr, Stockholm, Sweden Karolinska Inst, AstraZeneca, Dept Clin Neurosci, Stockholm, Sweden AstraZeneca, Oncol IMED, Macclesfield, Cheshire, EnglandWard, R. A.论文数: 0 引用数: 0 h-index: 0机构: AstraZeneca, Oncol IMED, Cambridge, England AstraZeneca, Oncol IMED, Macclesfield, Cheshire, EnglandWrigley, G. L.论文数: 0 引用数: 0 h-index: 0机构: AstraZeneca, Oncol IMED, Cambridge, England AstraZeneca, Oncol IMED, Macclesfield, Cheshire, EnglandYana, Y.论文数: 0 引用数: 0 h-index: 0机构: AstraZeneca, Asia & Emerging Markets IMED, Shanghai, Peoples R China AstraZeneca, Oncol IMED, Macclesfield, Cheshire, EnglandYates, J. W. T.论文数: 0 引用数: 0 h-index: 0机构: AstraZeneca, Oncol IMED, Cambridge, England AstraZeneca, Oncol IMED, Macclesfield, Cheshire, EnglandZhang, D.论文数: 0 引用数: 0 h-index: 0机构: AstraZeneca, Asia & Emerging Markets IMED, Shanghai, Peoples R China AstraZeneca, Oncol IMED, Macclesfield, Cheshire, EnglandZhang, Z.论文数: 0 引用数: 0 h-index: 0机构: AstraZeneca, Asia & Emerging Markets IMED, Shanghai, Peoples R China AstraZeneca, Oncol IMED, Macclesfield, Cheshire, England
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