Task-Rate-Related Neural Dynamics Using Wireless EEG to Assist Diagnosis and Intervention Planning for Preschoolers with ADHD Exhibiting Heterogeneous Cognitive Proficiency

被引：2

作者：

Chen, I-Chun ^{[1
,2
]}

Chen, Chia-Ling ^{[3
,4
]}

Chang, Chih-Hao ^{[5
,6
,7
]}

Fan, Zuo-Cian ^{[5
,6
,7
]}

Chang, Yang ^{[6
,7
,8
]}

Lin, Cheng-Hsiu ^{[9
]}

Ko, Li-Wei ^{[5
,6
,7
,8
,10
,11
]}

机构：

[1] Natl Yang Ming Chiao Tung Univ, Coll Biol Sci & Technol, Int PhD Program Interdisciplinary Neurosci, Hsinchu 30010, Taiwan

[2] Ton Yen Gen Hosp, Dept Phys Med & Rehabil, Hsinchu 30268, Taiwan

[3] Chang Gung Mem Hosp, Dept Phys Med & Rehabil, Taoyuan 33305, Taiwan

[4] Chang Gung Univ, Coll Med, Grad Inst Early Intervent, Taoyuan 33302, Taiwan

[5] Natl Yang Ming Chiao Tung Univ, Dept Biol Sci & Technol, Hsinchu 30010, Taiwan

[6] Natl Yang Ming Chiao Tung Univ, Brain Res Ctr, Hsinchu 30010, Taiwan

[7] Natl Yang Ming Chiao Tung Univ, Ctr Intelligent Drug Syst & Smart Biodevices IDS2, Hsinchu 30010, Taiwan

[8] Natl Yang Ming Chiao Tung Univ, Inst Bioinformat & Syst Biol, Hsinchu 30010, Taiwan

[9] Doctor Lins Psychiat Clin, Hsinchu 30069, Taiwan

[10] Natl Yang Ming Chiao Tung Univ, Inst Elect & Control Engn, Dept Elect & Elect Engn, Hsinchu 30010, Taiwan

[11] Kaohsiung Med Univ, Drug Dev & Value Creat Res Ctr, Dept Biomed Sci & Environm Biol, Kaohsiung 80708, Taiwan

来源：

JOURNAL OF PERSONALIZED MEDICINE | 2022年 / 12卷 / 05期

关键词：

ADHD; Conners Kiddie Continuous Performance Test (K-CPT); preschoolers; wireless electroencephalography; cognitive proficiency; ATTENTION-DEFICIT/HYPERACTIVITY DISORDER; DEFICIT HYPERACTIVITY DISORDER; CONTINUOUS PERFORMANCE-TEST; RESTING-STATE EEG; THETA/BETA RATIO; CLINICAL UTILITY; CHILDREN; MEMORY; ELECTROENCEPHALOGRAM; SUBTYPES;

D O I：

10.3390/jpm12050731

中图分类号：

R19 [保健组织与事业（卫生事业管理）];

学科分类号：

摘要：

This study used a wireless EEG system to investigate neural dynamics in preschoolers with ADHD who exhibited varying cognitive proficiency pertaining to working memory and processing speed abilities. Preschoolers with ADHD exhibiting high cognitive proficiency (ADHD-H, n = 24), those with ADHD exhibiting low cognitive proficiency (ADHD-L, n = 18), and preschoolers with typical development (TD, n = 31) underwent the Conners' Kiddie Continuous Performance Test and wireless EEG recording under different conditions (rest, slow-rate, and fast-rate task). In the slow-rate task condition, compared with the TD group, the ADHD-H group manifested higher delta and lower beta power in the central region, while the ADHD-L group manifested higher parietal delta power. In the fast-rate task condition, in the parietal region, ADHD-L manifested higher delta power than those in the other two groups (ADHD-H and TD); additionally, ADHD-L manifested higher theta as well as lower alpha and beta power than those with ADHD-H. Unlike those in the TD group, the delta power of both ADHD groups was enhanced in shifting from rest to task conditions. These findings suggest that task-rate-related neural dynamics contain specific neural biomarkers to assist clinical planning for ADHD in preschoolers with heterogeneous cognitive proficiency. The novel wireless EEG system used was convenient and highly suitable for clinical application.

引用

页数：17