Inference of molecular phylogenetic tree based on minimum model-based complexity method

被引:0
|
作者
Tanaka, H [1 ]
Ren, F [1 ]
Okayama, T [1 ]
Gojobori, T [1 ]
机构
[1] Tokyo Med & Dent Univ, Bunkyo Ku, Tokyo 113, Japan
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暂无
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
In this study starting with a newly introduced concept of data complexity ("empirical data complexity" ), we specify the concept of complexity more concretely in relation to mathematical modeling and introduce "model-based complexity (MBC)". Inductive inference based on the minimum model-based complexity method is then applied to the reconstruction of molecular evolutionary tree from DNA sequences. We find that minimum NBC method has good asymptotic property when DNA sequence lengths approach to infinite and compensates the bias of maximum likelihood method due to the difference of tree topology complexity. The efficiency of minimum MBC method for reconstruction of molecular tree is studied by computer simulation, and results suggest that this method is superior to the traditional maximum likelihood method or its modification by Akaike's AIC.
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页码:319 / 328
页数:10
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