Real-world experience of treatment decision-making in carotid stenosis in a neurovascular board

被引:8
|
作者
Rimmele, David Leander [1 ]
Larena-Avellaneda, Axel [5 ]
Alegiani, Anna C. [1 ]
Rosenkranz, Michael [6 ]
Schmidt, Nils Ole [2 ]
Regelsberger, Jan [2 ]
Hummel, Friedhelm C. [7 ,8 ]
Magnus, Tim [1 ]
Debus, Eike Sebastian [5 ]
Fiehler, Jens [3 ,4 ]
Gerloff, Christian [1 ]
Thomalla, Gotz [1 ]
机构
[1] Univ Klinikum Hamburg Eppendorf, Klin & Poliklin Neurol, Hamburg, Germany
[2] Univ klinikum Hamburg Eppendorf, Klin & Poliklin Neurochirurg, Hamburg, Germany
[3] Univ klinikum Hamburg Eppendorf, Kopf & Neurozentrum, Hamburg, Germany
[4] Univ klinikum Hamburg Eppendorf, Klin & Poliklin Neuroradiol Diagnost & Intervent, Diagnost Zentrum, Hamburg, Germany
[5] Univ Herzzentrum Hamburg, Klin Gefassmed, Hamburg, Germany
[6] Albertinen Krankenhaus, Klin Neurol & Neurol Fruhrehabilitat, Hamburg, Germany
[7] Swiss Fed Inst Technol EPFL, Campus Biotech, Geneva, Switzerland
[8] Clin Romande Readaptat, Sion, Switzerland
关键词
ARTERY STENOSIS; ENDARTERECTOMY; STROKE; ASSOCIATION; PREVENTION; GUIDELINES; DISEASE; RISK; AGE;
D O I
10.1212/WNL.0000000000004151
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Objective: To describe our experience with consensus-based decision-making for treatment of internal carotid artery (ICA) stenosis by neurologists, interventional neuroradiologists, vascular surgeons, and neurosurgeons in a multidisciplinary neurovascular board and to study adherence to treatment recommendations in the context of uncertainty with respect to the best treatment option. Methods: We established a multidisciplinary neurovascular board meeting twice a week with structured documentation of consensus decisions. Over a time period of 53 months, 614 cases with ICA stenosis were discussed, with 285 (46%) symptomatic and 279 (45%) asymptomatic cases. Results: Recommendation for symptomatic ICA stenosis was revascularization in 76%, medical management alone in 8%, and further diagnostics in 16%. For asymptomatic ICA stenosis, recommendation was randomization in a clinical trial in 29%, revascularization in 27%, medical management alone in 23%, and further diagnostics in 22%. Treatment recommendations were followed in 94% of symptomatic ICA stenosis and 69% of asymptomatic ICA stenosis. Patients in whom carotid artery stenting was recommended for revascularization were younger and showed a higher rate of severe ($ 70%) ICA stenosis. Conclusions: Interdisciplinary board decisions are a helpful and transparent tool to assure adherence to guideline recommendations, and to provide consensus-based individualized treatment strategies in clinical practice in the absence of unequivocal evidence.
引用
收藏
页码:399 / 407
页数:9
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