Eculizumab for the treatment of an atypical hemolytic uremic syndrome with mutations in complement factor I and C3

被引:3
|
作者
Ferreira, Emanuel [1 ,2 ]
Oliveira, Nuno [1 ,2 ]
Marques, Maria [1 ,2 ]
Francisco, Luis [2 ,3 ]
Santos, Ana [1 ,2 ]
Carreira, Armando [1 ,2 ]
Campos, Mario [1 ,4 ]
机构
[1] Ctr Hosp Coimbra, Serv Nefrol, Rua Buxo,Lote 17, P-3040792 Coimbra, Portugal
[2] Univ Coimbra, Hosp Geral, Rua Buxo,Lote 17, P-3040792 Coimbra, Portugal
[3] Ctr Hosp Coimbra, Serv Hematol, Coimbra, Portugal
[4] Univ Coimbra, Hosp Univ Coimbra, Coimbra, Portugal
来源
NEFROLOGIA | 2016年 / 36卷 / 01期
关键词
AHUS;
D O I
10.1016/j.nefro.2015.07.007
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:72 / 75
页数:4
相关论文
共 50 条
  • [1] Efficacy of Eculizumab in Coexisting Complement C3 Glomerulopathy and Atypical Hemolytic Uremic Syndrome
    Busutti, Marco
    Diomedi-Camassei, Francesca
    Donadelli, Roberta
    Mele, Caterina
    Emma, Francesco
    Vivarelli, Marina
    KIDNEY INTERNATIONAL REPORTS, 2021, 6 (02): : 534 - 537
  • [2] Mutations in complement C3 predispose to development of atypical hemolytic uremic syndrome
    Fremeaux-Bacchi, Veronique
    Miller, Elizabeth C.
    Liszewski, M. Kathryn
    Strain, Lisa
    Blouin, Jacques
    Brown, Alison L.
    Moghal, Nadeem
    Kaplan, Bernard S.
    Weiss, Robert A.
    Lhotta, Karl
    Kapur, Gaurav
    Mattoo, Tej
    Nivet, Hubert
    Wong, William
    Gie, Sophie
    de Ligny, Bruno Hurault
    Fischbach, Michel
    Gupta, Ritu
    Hauhart, Richard
    Meunier, Vincent
    Loirat, Chantal
    Dragon-Durey, Marie-Agnes
    Fridman, Wolf H.
    Janssen, Bert J. C.
    Goodship, Timothy H. J.
    Atkinson, John P.
    BLOOD, 2008, 112 (13) : 4948 - 4952
  • [3] Complement C3 mutation causing atypical hemolytic uremic syndrome successfully treated with eculizumab
    Ellithi, Moataz
    Shahid, Mahum
    Abdullah, Hafez Mohammad
    Bleeker, Jonathan
    HEMATOLOGY TRANSFUSION AND CELL THERAPY, 2021, 43 (03) : 364 - 367
  • [4] Mutations of C3 in Atypical Hemolytic Uremic Syndrome (aHUS)
    Miller, Elizabeth C.
    Liszewski, M. Kathryn
    Gupta, Ritu
    Hauhart, Richard
    Fremeaux-Bacchi, Veronique
    Goodship, Timothy
    Atkinson, John
    FASEB JOURNAL, 2008, 22
  • [5] The molecular and structural bases for the association of complement C3 mutations with atypical hemolytic uremic syndrome
    Martinez-Barricarte, Ruben
    Heurich, Meike
    Lopez-Perrote, Andres
    Tortajada, Agustin
    Pinto, Sheila
    Lopez-Trascasa, Margarita
    Sanchez-Corral, Pilar
    Morgan, B. Paul
    Llorca, Oscar
    Harris, Claire L.
    Rodriguez de Cordoba, Santiago
    MOLECULAR IMMUNOLOGY, 2015, 66 (02) : 263 - 273
  • [6] Mutations in complement factor I predispose to development of atypical hemolytic uremic syndrome
    Kavanagh, D
    Kemp, EJ
    Mayland, E
    Winney, RJ
    Duffield, JS
    Warwick, G
    Richards, A
    Ward, R
    Goodship, JA
    Goodship, THJ
    JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2005, 16 (07): : 2150 - 2155
  • [7] Successful Treatment of Atypical Hemolytic Uremic Syndrome with the Complement Inhibitor Eculizumab
    Nuernberger, Jens
    Witzke, Oliver
    Rother, Russell P.
    Philipp, Thomas
    Vester, Udo
    Baba, Hideo
    Zimmerhackl, Lothar Bemd
    Kribben, Andreas
    BLOOD, 2008, 112 (11) : 800 - 800
  • [8] Complement Inhibitor Eculizumab in Atypical Hemolytic Uremic Syndrome
    Mache, Christoph J.
    Acham-Roschitz, Birgit
    Fremeaux-Bacchi, Veronique
    Kirschfink, Michael
    Zipfel, Peter F.
    Roedl, Siegfried
    Vester, Udo
    Ring, Ekkehard
    CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2009, 4 (08): : 1312 - 1316
  • [9] Mapping interactions between complement C3 and regulators using mutations in atypical hemolytic uremic syndrome
    Schramm, Elizabeth C.
    Roumenina, Lubka T.
    Rybkine, Tania
    Chauvet, Sophie
    Vieira-Martins, Paula
    Hue, Christophe
    Maga, Tara
    Valoti, Elisabetta
    Wilson, Valerie
    Jokiranta, Sakari
    Smith, Richard J. H.
    Noris, Marina
    Goodship, Tim
    Atkinson, John P.
    Fremeaux-Bacchi, Veronique
    BLOOD, 2015, 125 (15) : 2359 - 2369
  • [10] Eculizumab treatment of atypical hemolytic uremic syndrome
    Kaplan, Bernard S.
    Ruebner, Rebecca L.
    Copelovitch, Lawrence
    EXPERT OPINION ON ORPHAN DRUGS, 2013, 1 (02): : 167 - 176