Stroke prevention in sickle cell disease

被引：19
|
作者：
Adams, RJ [1 ]
机构：
[1] Med Coll Georgia, Dept Neurol, Augusta, GA 30912 USA
来源：
CURRENT OPINION IN HEMATOLOGY | 2000年 / 7卷 / 02期
关键词：
D O I：
10.1097/00062752-200003000-00005
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Neurological complications, especially stroke, have long been recognized in sickle cell disease. Advances in care have increased the life expectancy of such patients, and recent information has better established the epidemiology of stroke. Prevention of stroke in children has been established in a clinical trial. Silent brain lesions revealed by MRI are common and are associated with impairments of cognitive function. Transfusion remains the primary mode of prevention and treat ment for stroke, although interest is increasing in hydroxyurea; however, there are no data regarding its efficacy. (C) 2000 Lippincott Williams & Wilkins, Inc.
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收藏
页码：101 / 105
页数：5
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