Modulation of bone remodeling by active vitamin D: its role in the treatment of osteoporosis

被引：8
|
作者：
Ikeda, K
Ogata, E
机构：
[1] Natl Inst Lonev Sci, Dept Geriatr Res, Aichi 4748522, Japan
[2] Japanese Fdn Canc Res, Canc Inst Hosp, Tokyo 1708455, Japan
来源：
MECHANISMS OF AGEING AND DEVELOPMENT | 2000年 / 116卷 / 2-3期
关键词：
active vitamin D; osteoporosis; bone resorption; bone formation;
D O I：
10.1016/S0047-6374(00)00115-9
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Active vitamin D drugs are used for the treatment of osteoporosis in a number of countries, including Japan. However, their use is controversial. Here, we briefly discuss two issues that are important for understanding the role of active vitamin D (rather than plain vitamin D) in the treatment of osteoporosis: (1) whether or not its skeletal effects are mediated solely through its effects on intestinal calcium absorption in calcium- and vitamin D-replete states, and (2) how it modulates the bone remodeling process. (C) 2000 Elsevier Science Ireland Ltd. All rights reserved.
引用
收藏
页码：103 / 111
页数：9
相关论文
共 50 条
  • [1] Active vitamin D and its analogs as drugs for the treatment of osteoporosis: advantages and problems
    Yasuho Nishii
    Journal of Bone and Mineral Metabolism, 2002, 20 : 57 - 65
  • [2] Active vitamin D and its analogs as drugs for the treatment of osteoporosis: advantages and problems
    Nishii, Y
    JOURNAL OF BONE AND MINERAL METABOLISM, 2002, 20 (02) : 57 - 65
  • [3] The role of vitamin D in the prevention and treatment of osteoporosis
    Elliott M.E.
    Nolan N.M.
    Clinical Reviews in Bone and Mineral Metabolism, 2004, 2 (4): : 373 - 388
  • [4] The role of vitamin D in the treatment of osteoporosis in the elderly
    Pfeifer, M.
    Minne, H. W.
    OSTEOLOGIE, 2008, 17 (02) : 39 - 45
  • [5] The role of vitamin D in the pathogenesis and treatment of osteoporosis
    Gallagher, JC
    JOURNAL OF RHEUMATOLOGY, 1996, 23 : 15 - 18
  • [6] Role of calcium and vitamin D in the treatment of osteoporosis
    Recker, R. R.
    Cannata Andia, J. B.
    del Pino Montes, J.
    Diaz Curiel, M.
    Nogues i Solan, X.
    Valdes Llorca, C.
    Sosa Henriquez, M.
    Gomez de Tejada Romero, M. J.
    REVISTA DE OSTEOPOROSIS Y METABOLISMO MINERAL, 2010, 2 (01) : 61 - 72
  • [7] Role of nutritional vitamin D in osteoporosis treatment
    Hou, Yi-Chou
    Wu, Chia-Chao
    Liao, Min-Tser
    Shyu, Jia-Fwu
    Hung, Chi-Feng
    Yen, Tzung-Hai
    Lu, Chien-Lin
    Lu, Kuo-Cheng
    CLINICA CHIMICA ACTA, 2018, 484 : 179 - 191
  • [8] Vitamin D and its metabolites in the treatment of osteoporosis
    Burckhardt, P
    Lamy, O
    OSTEOPOROSIS INTERNATIONAL, 1998, 8 (Suppl 2) : S40 - S44
  • [9] Vitamin D and its Metabolites in the Treatment of Osteoporosis
    P. Burckhardt
    O. Lamy
    Osteoporosis International, 1998, 8 : S40 - S44
  • [10] Rationale for active vitamin D and analogs in the treatment of osteoporosis
    Nishii, Y
    JOURNAL OF CELLULAR BIOCHEMISTRY, 2003, 88 (02) : 381 - 386
12345