Sleep and alertness disturbance and substance use disorders: A bi-directional relation

被引：33
|
作者：
Roehrs, Timothy [1 ,2 ,3 ]
Sibai, Mohammad [1 ,3 ]
Roth, Thomas [1 ,2 ]
机构：
[1] Henry Ford Hlth Syst, Sleep Med, Detroit, MI USA
[2] Wayne State Univ, Dept Psychiat & Behav Neurosci, SOM, Detroit, MI 48207 USA
[3] Univ Detroit Mercy, Dept Psychol, Detroit, MI 48221 USA
来源：
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR | 2021年 / 203卷
关键词：
Substance use disorder; Sleep disturbance; Excessive daytime sleepiness; Polysomnography; Multiple sleep latency testing; ADENOSINE A(2A) RECEPTORS; EYE-MOVEMENT SLEEP; RISK-FACTOR; MARIJUANA WITHDRAWAL; PRIMARY ALCOHOLISM; INSOMNIA SEVERITY; LABORATORY MODEL; NIGHTLY ZOLPIDEM; MORPHINE; COCAINE;
D O I：
10.1016/j.pbb.2021.173153
中图分类号：
B84 [心理学]; C [社会科学总论]; Q98 [人类学];
学科分类号：
03 ; 0303 ; 030303 ; 04 ; 0402 ;
摘要：
The majority of the literature describing the relation of sleep/alertness disturbance and substance use disorders (SUD) has focused on the disruptive effects of substances with abuse liability on sleep and alertness. Rarely have studies or literature reviews assessed or discussed how sleep/alertness disturbance affects substance use. This paper focuses on the sleep/alertness disturbance side of the relation. We argue that the relation is bi-directional and review evidence showing that sleep/alertness disturbance affects all phases of the addiction cycle, including the initiation, maintenance and relapse of SUD. We review a variety of substances across all phases of the addiction cycle and conclude sleep/alertness disturbance is a critical factor in both understanding and treating SUD.
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页数：8
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