Making up 'Vulnerable' People: Human Subjects and the Subjective Experience of Medical Experiment

This paper explores how 'the human subject' was figured historically and expands the interpretive range available to historians for understanding the subjective experiences of people who have served in medical experiments in the past. We compare LSD studies on healthy 'volunteers' conducted in two experimental settings in the 1950s: the US National Institutes of Mental Health's (NIMH) Addiction Research Center (ARC) Lexington, Kentucky and the NIH Clinical Center (NIHCC) in Bethesda, Maryland. Sources consist of oral history interviews, transcripts and archival documents including photographs and records. Political priorities and historical contingencies relevant for crystalising the expert domain of modern bioethics, especially the 1960s US Civil Rights movement, were central for producing the 'vulnerability' attributed to the modern figure of the 'human subject'. Using Ian Hacking's historical ontology approach, we suggest how this figure of the 'vulnerable human subject' affected historical actors' self-understandings while foreclosing paths of historical inquiry and interpretation.