Chondrogenesis. of human mesenchymal stem cells

被引：0
|
作者：
Ito, T [1 ]
Hattori, T [1 ]
Amano, K [1 ]
Nakano, A [1 ]
Kamakura, M [1 ]
机构：
[1] Teikyo Univ, Sch Med, Tokyo 173, Japan
来源：
7TH ANNUAL MEETING OF THE EUROPEAN HAEMATOLOGY ASSOCIATION | 2002年
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D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Bone marrow mesenchymal stem cells (MSCs) were tested their ability to undergo chondrogenesis. MSCs in a dish or a tube culture, treated with TGF-beta3 followed by thyroxine, expressed the morphology and histochemistry of cartilagenous tissues. Pellets grown in tube culture stained more intensely by alcian-blue, safranin-O, and azan-mallory. The factors to promote chondrogenesis were; tube culture, hypoxic culture, high-glucose DMEM, TGF-beta3, thyroxine, and dexamethasone. MSC-based cell therapy might be applicable for cartilage repair.
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页码：39 / 42
页数：4
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