New silyl ether reagents for the absolute stereochemical determination of secondary alcohols

被引：16
|
作者：
Williamson, RT
Sosa, ACB
Mitra, A
Seaton, PJ
Weibel, DB
Schroeder, FC
Meinwald, J
Koehn, FE
机构：
[1] Wyeth Res, Pearl River, NY 10965 USA
[2] Manhattan Coll, Coll Mt St Vincent, Dept Chem, Bronx, NY 10471 USA
[3] Manhattan Coll, Coll Mt St Vincent, Dept Biochem, Bronx, NY 10471 USA
[4] Univ N Carolina, Dept Chem, Wilmington, NC 28403 USA
[5] Cornell Univ, Dept Chem & Biol Chem, Ithaca, NY 14853 USA
来源：
ORGANIC LETTERS | 2003年 / 5卷 / 10期
关键词：
D O I：
10.1021/ol034418o
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
[GRAPHICS] Herein we report a new set of silyl ether reagents for determining the enantiomeric purity and absolute stereochemistry of secondary alcohols. These derivatives are easily synthesized, provide straightforward spectroscopic results, and allow for facile recovery of the original chiral alcohol.
引用
收藏
页码：1745 / 1748
页数：4
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