Study on molecular recognition of amino acid esters by novel tetraphenylporphinatozinc complex modified with chiral tyrosine

被引：0

作者：

Wang, SJ ^{[1
]}

Ruan, WJ ^{[1
]}

Luo, DB ^{[1
]}

Zhu, ZA ^{[1
]}

机构：

[1] Nankai Univ, Dept Chem, Tianjin 300071, Peoples R China

来源：

ACTA CHIMICA SINICA | 2004年 / 62卷 / 21期

关键词：

chiral zinc porphyrin; chiral amino acid ester; chiral molecular recognition; circular dichroism spectra; molecular mechanics;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

One kind of novel zinc prophyrin complex modified by L-BocTyrosine was synthesized and characterized. Molecular recognitions of four pairs of amino acid esters by the chiral zinc porphyrin have been investigated with UV-Vis spectral method. The results show that association constants of the recognition process are all in the order of K-D > K-L, following the order K(PheOMe) > K(AIaOMe) > K(ValOMe) > K(LeuOMe). Circular dichroism spectra have been used to explain chiral molecular recognition. In addition, the conformations with minimal energy of host and host-guest molecular systems were sought by molecular dynamics method. Experimental essence was more deeply discussed by theoretical calculation.

引用

页码：2165 / 2170

页数：6

共 18 条

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