NOTCH1 mutational status in chronic lymphocytic leukaemia: clinical relevance of subclonal mutations and mutation types

被引：17

作者：

D'Agaro, Tiziana ^{[1
]}

Bittolo, Tamara ^{[1
]}

Bravin, Vanessa ^{[1
]}

Dal Bo, Michele ^{[1
]}

Pozzo, Federico ^{[1
]}

Bulian, Pietro ^{[1
]}

Rossi, Francesca M. ^{[1
]}

Zucchetto, Antonella ^{[1
]}

Degan, Massimo ^{[1
]}

D'Arena, Giovanni ^{[2
]}

Chiarenza, Annalisa ^{[3
]}

Zaja, Francesco ^{[4
]}

Pozzato, Gabriele ^{[5
]}

Di Raimondo, Francesco ^{[3
]}

Rossi, Davide ^{[6
,7
]}

Gaidano, Gianluca ^{[8
]}

Del Poeta, Giovanni ^{[9
,10
]}

Gattei, Valter ^{[1
]}

Bomben, Riccardo ^{[1
]}

机构：

[1] IRCCS, Ctr Riferimento Oncol, Clin & Expt Oncohaematol Unit, Aviano, PN, Italy

[2] IRCCS, Ctr Riferimento Oncol Basilicata, Oncohaematol Dept, Rionero In Vulture, Italy

[3] Ferrarotto Hosp, Div Haematol, Catania, Italy

[4] Azienda Osped Univ S Maria Misericordia, Ctr Trapianti & Terapie Cellulari Carlo Melzi DIS, Clin Ematol, Udine, Italy

[5] Univ Trieste, Maggiore Gen Hosp, Dept Internal Med & Haematol, Trieste, Italy

[6] Inst Oncol Res, Haematol, Bellinzona, Switzerland

[7] Oncol Inst Southern Switzerland, Bellinzona, Switzerland

[8] Univ Piemonte Orientale, Dept Translat Med, Div Haematol, Novara, Italy

[9] S Eugenio Hosp, Div Haematol, Rome, Italy

[10] Univ Tor Vergata, Rome, Italy

来源：

BRITISH JOURNAL OF HAEMATOLOGY | 2018年 / 182卷 / 04期

关键词：

chronic lymphocytic leukaemia; NOTCH1; mutations; progression-free survival; overall survival; RECURRENT MUTATIONS; SURVIVAL;

D O I：

10.1111/bjh.14843

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：597 / 602

页数：6

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