Efficacy and tolerability of a lotion containing triethyl citrate, ethyl linoleate, and GT peptide-10 in the adjuvant treatment of hidradenitis suppurativa: Real-life data

被引：2

作者：

Skroza, N. ^{[1
]}

Mambrin, A. ^{[1
]}

Tolino, E. ^{[1
]}

Marchesiello, A. ^{[1
]}

Proietti, I ^{[1
]}

Bernardini, N. ^{[1
]}

Potenza, C. ^{[1
]}

机构：

[1] Sapienza Univ Rome, Fiorini Hosp, Dept Med Surg Sci & Biotechnol, Dermatol Unit Daniele Innocenzi, Via Firenze Snc, I-04019 Polo Pontino, Terracina, Italy

来源：

DERMATOLOGIC THERAPY | 2018年 / 31卷 / 04期

关键词：

hidradens suppurativa; topical therapy; triethyl citrate ethyl linoleate G -peptide 10; ACNE-VULGARIS;

D O I：

10.1111/dth.12599

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Hidradenitis suppurativa (HS) is a chronic disorder of terminal follicular epithelium in the apocrine gland-bearing areas. The long term therapy is based mainly on topical and/or systemic antibiotic use that could result in antibiotic resistance. The aim of our study was to present the real-life experience based on the efficacy and tolerability of a novel lotion containing triethyl-citrate, ethyl-linoleate, and g-peptide-10 in the treatment of mild to moderate HS that has already shown effectiveness in acne treatment. This was an open-label study on 30 patients of both sexes affected by HS. Patients were divided into two groups: 15 with Hurley I and 15 with Hurley II-III. The subjects were treated with the topical lotion, three-times-daily for eight weeks, with control at 4 (T1) and eight weeks (T-2). Any other concomitant treatment (both topical and/or systemic) was avoided during study period. Improvement was observed in both Sartorius score grading system and inflammatory and noninflammatory lesion counts. The novel lotion has proved to be effective and well-tolerated topical agent alone or in association with other topical and/or systemic tratments in HS, without side effects

引用

页数：4