Studies of the skin permeation of lipophilic drugs: paclitaxel

被引:2
|
作者
Khandavilli, S. [1 ]
Panchagnula, R. [1 ]
机构
[1] Natl Inst Pharmaceut Educ & Res, Dept Pharmaceut, Mohali, India
来源
PHARMAZIE | 2007年 / 62卷 / 06期
关键词
D O I
10.1691/ph.2007.6.6044
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
The objective of this investigation was to develop and validate skin permeation methodology for a highly lipophilic drug with respect to sink conditions and intactness of barrier during the course of experiment, using water permeation and trans epidermal water loss as tools.
引用
收藏
页码:471 / 473
页数:3
相关论文
共 50 条
  • [1] PERMEATION OF LIPOPHILIC DRUGS THROUGH SYNTHETIC ELASTOMERS
    BRUCK, SD
    KOJIMA, M
    KADOMA, Y
    MASUHARA, E
    MEDICAL PROGRESS THROUGH TECHNOLOGY, 1983, 10 (03) : 161 - 169
  • [2] Mechanism of transdermal permeation promotion of lipophilic drugs by ethosomes
    Yang, Li
    Wu, Lifang
    Wu, Dongze
    Shi, Deshun
    Wang, Tai
    Zhu, Xiaoliang
    INTERNATIONAL JOURNAL OF NANOMEDICINE, 2017, 12 : 3357 - 3364
  • [3] COMBINED EFFECT OF D-LIMONENE PRETREATMENT AND TEMPERATURE ON THE RAT SKIN PERMEATION OF LIPOPHILIC AND HYDROPHILIC DRUGS
    OHARA, N
    TAKAYAMA, K
    NAGAI, T
    BIOLOGICAL & PHARMACEUTICAL BULLETIN, 1995, 18 (03) : 439 - 442
  • [4] Supersaturation: Enhancement of skin penetration and permeation of a lipophilic drug
    Moser, K
    Kriwet, K
    Froehlich, C
    Kalia, YN
    Guy, RH
    PHARMACEUTICAL RESEARCH, 2001, 18 (07) : 1006 - 1011
  • [5] Supersaturation: Enhancement of Skin Penetration and Permeation of a Lipophilic Drug
    Katrin Moser
    Katrin Kriwet
    Christiane Froehlich
    Yogeshvar N. Kalia
    Richard H. Guy
    Pharmaceutical Research, 2001, 18 : 1006 - 1011
  • [6] Chitosan-chondroitin composite films: Comparison with in vitro skin permeation data of hydrophilic and lipophilic drugs
    Rana, Vikas
    Tiwary, Ashok Kumar
    Jain, Subheet
    Singh, Dhandeep
    IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH, 2007, 6 (04): : 231 - 242
  • [7] ALTERED SKIN PERMEATION OF A HIGHLY LIPOPHILIC MOLECULE - TETRAHYDROCANNABINOL
    TOUITOU, E
    FABIN, B
    INTERNATIONAL JOURNAL OF PHARMACEUTICS, 1988, 43 (1-2) : 17 - 22
  • [8] Effect of combination of hydrophilic and lipophilic permeation enhancers on the skin permeation of kahalalide F
    Shah, Punit P.
    Desai, Pinaki R.
    Patlolla, Ram
    Klevans, Larry
    Singh, Mandip
    JOURNAL OF PHARMACY AND PHARMACOLOGY, 2014, 66 (06) : 760 - 768
  • [9] Confocal Raman studies of the skin permeation of an anti-inflammatory tocopheryl phosphate lipophilic complex
    Moore, J.
    Bi, X.
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2007, 127 : S60 - S60
  • [10] EVALUATION OF EXCISED LOACH SKIN FOR STUDIES ON TRANSDERMAL PERMEATION OF DRUGS INVITRO
    WATANABE, Y
    HONGO, S
    MATSUMOTO, M
    YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 1989, 109 (09): : 656 - 661