A Colorimetric Sensor Array for the Detection of the Date-Rape Drug γ-Hydroxybutyric Acid (GHB): A Supramolecular Approach

被引：60

作者：

Baumes, Laurent A. ^{[1
]}

Sogo, Mireia Buaki ^{[1
]}

Montes-Navajas, Pedro ^{[1
]}

Corma, Avelino ^{[1
]}

Garcia, Hermenegildo ^{[1
]}

机构：

[1] Univ Politecn Valencia, CSIC, Inst Tecnol Quim, Valencia 46022, Spain

来源：

CHEMISTRY-A EUROPEAN JOURNAL | 2010年 / 16卷 / 15期

关键词：

cucurbiturils; drug detection; host-guest systems; sensors; supramolecular chemistry; RATIONAL DESIGN; DYES; IDENTIFICATION; ENCAPSULATION; INTOXICATION; METHODOLOGY; COMPLEXES; ABUSE; COMA; TALE;

D O I：

10.1002/chem.200903127

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

gamma-Hydroxybutyric acid (GHB), a colourless, odourless and tasteless chemical, has become one of the most dangerous illicit drugs of abuse today. At low doses, this drug is a central nervous system depressant that reduces anxiety and produces euphoria and relaxation, sedating the recipient. There is an urgent need for simple, easy-to-use sensors for GHB in solution. Here, we present a colorimetric sensor array based on supramolecular host guest complexes of fluorescent dyes with organic capsules (cucurbiturils) for the detection of GHB.

引用

页码：4489 / 4495

页数：7

共 25 条

[1] Colorimetric paper sensor for visual detection of date-rape drug γ-hydroxybutyric acid (GHB)
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Lim, Jaewoo
Seo, Seungbeom
Kang, Taejoon
Jung, Juyeon
Lee, Kyu-Sun
Kim, Hyungjun
Lim, Eun-Kyung
SENSORS AND ACTUATORS B-CHEMICAL, 2021, 347
[2] Is gamma-hydroxybutyric acid (GHB) really used in rave-parties and as a date-rape drug in France?
Deveaux, M
Renet, S
Renet, V
Gaulier, JM
Kintz, P
Verstraete, A
Gosset, D
ACTA CLINICA BELGICA, 2002, 57 : 37 - 40
[3] gamma-Hydroxybutyric acid (GHB) as date rape drug in sexual assaults
Loddo, Catia M.
Beike, Justus
Rothschild, Markus A.
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[4] Sensor detects date-rape drug in seconds
Chang Young-Tae
TRAC-TRENDS IN ANALYTICAL CHEMISTRY, 2014, 58 : 5 - 5
[5] Identification of the date-rape drug GHB and its precursor GBL by Raman spectroscopy
Brewster, Victoria L.
Edwards, Howell G. M.
Hargreaves, Michael D.
Munshi, Tasnim
DRUG TESTING AND ANALYSIS, 2009, 1 (1-2) : 25 - 31
[6] Gamma-hydroxybutyric acid (GHB): more than a date rape drug, a potentially addictive drug
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Novarin, Johanne
Megarbane, Bruno
Cottencin, Olivier
Dally, Sylvain
Lowenstein, William
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PRESSE MEDICALE, 2009, 38 (10): : 1526 - 1538
[7] Bifunctionalized Gold Nanoparticles for the Colorimetric Detection of the Drug γ-Hydroxybutyric Acid (GHB) in Beverages
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Costero, Ana M.
Gil, Salvador
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CHEMOSENSORS, 2021, 9 (07)
[8] Field-test of a date-rape drug detection device
Quest, Dale W.
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JOURNAL OF ANALYTICAL TOXICOLOGY, 2007, 31 (06) : 354 - 357
[9] Superwettable microchip for visual detection of date-rape drug in beverages
Li, Zhenping
Xu, Hao
Du, Yukun
Huang, Zhongyu
Li, Jing
Liu, Lian
Dong, Ying
Yang, Xiao-Yu
SENSORS AND ACTUATORS B-CHEMICAL, 2025, 423
[10] Development of a fluorescent sensor for illicit date rape drug GHB
Zhai, Duanting
Tan, Yong Qiao Elton
Xu, Wang
Chang, Young-Tae
CHEMICAL COMMUNICATIONS, 2014, 50 (22) : 2904 - 2906

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