CDK12-kinase activity controls G1/S progression by regulating optimal transcription of core DNA replication genes.

被引:0
|
作者
Manavalan, A. Chirackal [1 ]
Pilarova, K. [1 ]
Kluge, M. [2 ]
Bartholomeeusen, K. [1 ]
Opplet, J. [1 ]
Khirsariya, P. [3 ]
Paruch, K. [3 ]
Krejci, L. [4 ]
Friedel, C. [2 ]
Blazek, D. [1 ]
机构
[1] Masaryk Univ, Mol Med, Cent European Inst Technol CEITEC, Brno, Czech Republic
[2] Ludwig Maximilians Univ Munchen, Inst Informat, Munich, Germany
[3] Masaryk Univ, Dept Chem, CZ Openscreen, Fac Sci, Brno, Czech Republic
[4] Masaryk Univ, Natl Ctr Biomol Res, Brno, Czech Republic
关键词
D O I
暂无
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
P2192
引用
收藏
页数:1
相关论文
共 33 条
  • [1] CDK12 controls G1/S progression by regulating RNAPII processivity at core DNA replication genes
    Manavalan, Anil Paul Chirackal
    Pilarova, Kveta
    Kluge, Michael
    Bartholomeeusen, Koen
    Rajecky, Michal
    Oppelt, Jan
    Khirsariya, Prashant
    Paruch, Kamil
    Krejci, Lumir
    Friedel, Caroline C.
    Blazek, Dalibor
    EMBO REPORTS, 2019, 20 (09)
  • [2] Regulation of the G1/S Transition in Hepatocytes: Involvement of the Cyclin-Dependent Kinase Cdk1 in the DNA Replication
    Corlu, Anne
    Loyer, Pascal
    INTERNATIONAL JOURNAL OF HEPATOLOGY, 2012, 2012
  • [3] Down-regulation of Cdk1 activity in G1 coordinates the G1/S gene expression programme with genome replication
    Garcia-Blanco, Natalia
    Moreno, Sergio
    CURRENT GENETICS, 2019, 65 (03) : 685 - 690
  • [4] Down-regulation of Cdk1 activity in G1 coordinates the G1/S gene expression programme with genome replication
    Natalia García-Blanco
    Sergio Moreno
    Current Genetics, 2019, 65 : 685 - 690
  • [5] CDK activity antagonizes Whi5, an inhibitor of G1/S transcription in yeast
    Costanzo, M
    Nishikawa, JL
    Tang, XL
    Millman, JS
    Schub, O
    Breitkreuz, K
    Dewar, D
    Rupes, I
    Andrews, B
    Tyers, M
    CELL, 2004, 117 (07) : 899 - 913
  • [6] Linking DNA replication checkpoint to MBF cell-cycle transcription reveals a distinct class of G1/S genes
    de Oliveira, Francisco M. Bastos
    Harris, Michael R.
    Brazauskas, Pijus
    de Bruin, Robertus A. M.
    Smolka, Marcus B.
    EMBO JOURNAL, 2012, 31 (07): : 1798 - 1810
  • [7] The DNA replication checkpoint directly regulates MBF-dependent G1/S transcription
    Dutta, Chaitali
    Patel, Prasanta K.
    Rosebrock, Adam
    Oliva, Anna
    Leatherwood, Janet
    Rhind, Nicholas
    MOLECULAR AND CELLULAR BIOLOGY, 2008, 28 (19) : 5977 - 5985
  • [8] RACK1 regulates G1/S progression by suppressing Src kinase activity
    Mamidipudi, V
    Zhang, J
    Lee, KC
    Cartwright, CA
    MOLECULAR AND CELLULAR BIOLOGY, 2004, 24 (15) : 6788 - 6798
  • [9] G1/S CDK is inhibited to restrain mitotic onset when DNA replication is blocked in fission yeast
    Zarzov, P
    Decottignies, A
    Baldacci, G
    Nurse, P
    EMBO JOURNAL, 2002, 21 (13): : 3370 - 3376
  • [10] MITOTIC DELAY AND REGULATING EVENTS OF PLANT CELL PROLIFERATION - DNA REPLICATION BY A G1/S POPULATION
    KOVACS, CJ
    VANTHOF, J
    RADIATION RESEARCH, 1971, 48 (01) : 95 - +