Amyloid Imaging in Early Detection of Alzheimer's Disease

被引：22
|
作者：
Nordberg, Agneta [1 ]
机构：
[1] Karolinska Univ Hosp Huddinge, Karolinska Inst, Div Alzheimer Neurobiol, Geriatr Clin, SE-14186 Stockholm, Sweden
来源：
NEURODEGENERATIVE DISEASES | 2010年 / 7卷 / 1-3期
基金：
瑞典研究理事会;
关键词：
Alzheimer's disease; Amyloid imaging; Positron emission tomography; Pittsburgh compound B; Mild cognitive impairment; Early diagnostic markers; CSF biomarkers; PITTSBURGH COMPOUND-B; MILD COGNITIVE IMPAIRMENT; PET; DEPOSITION; C-11-PIB; BINDING;
D O I：
10.1159/000289223
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Amyloid imaging has provided evidence for early detection of amyloid (A beta) load in prodromal Alzheimer's disease (AD). Several amyloid tracers have been developed for studies with positron emission tomography (PET). Early detection of at-risk subjects will be important in the future for a successful treatment of AD. The high A beta load in the brain measured by PET in patients with mild cognitive impairment that later will convert to AD suggests early, significant, ongoing pathological processes prior to cognitive impairment. PET A beta imaging will also be used for discrimination of AD from other dementia disorders, as well for the evaluation of anti-A beta drugs. Copyright (C) 2010 S. Karger AG, Basel
引用
收藏
页码：136 / 138
页数：3
相关论文
共 50 条
  • [1] Amyloid imaging in Alzheimer's disease
    Nordberg, Agneta
    [J]. NEUROPSYCHOLOGIA, 2008, 46 (06) : 1636 - 1641
  • [2] Amyloid imaging in Alzheimer's disease
    Nordberg, Agneta
    [J]. CURRENT OPINION IN NEUROLOGY, 2007, 20 (04) : 398 - 402
  • [3] Early Detection of Alzheimer's Disease with PET Imaging
    Berti, V.
    Osorio, R. S.
    Mosconi, L.
    Li, Y.
    De Santi, S.
    de Leon, M. J.
    [J]. NEURODEGENERATIVE DISEASES, 2010, 7 (1-3) : 131 - 135
  • [4] Early Detection of Amyloid β Pathology in Alzheimer's Disease by Molecular MRI
    Dong, Celia M.
    Guo, Audrey S.
    To, Anthea
    Chan, Kannie W. Y.
    Chow, Aviva S. F.
    Bian, Liming
    Leong, Alex T. L.
    Wu, Ed X.
    [J]. 42ND ANNUAL INTERNATIONAL CONFERENCES OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY: ENABLING INNOVATIVE TECHNOLOGIES FOR GLOBAL HEALTHCARE EMBC'20, 2020, : 1100 - 1103
  • [5] Detection of amyloid β oligomers toward early diagnosis of Alzheimer's disease
    Hwang, Soyoon Sarah
    Chan, Hon
    Sorci, Mirco
    van Deventer, James
    Wittrup, Dane
    Belfort, Georges
    Walt, David
    [J]. ANALYTICAL BIOCHEMISTRY, 2019, 566 : 40 - 45
  • [6] In vivo amyloid imaging in Alzheimer’s disease
    H. I. Sair
    P. M. Doraiswamy
    J. R. Petrella
    [J]. Neuroradiology, 2004, 46 : 93 - 104
  • [7] Clinical amyloid imaging in Alzheimer's disease
    Herholz, Karl
    Ebmeier, Klaus
    [J]. LANCET NEUROLOGY, 2011, 10 (07): : 667 - 670
  • [8] In vivo amyloid imaging in Alzheimer's disease
    Sair, HI
    Doraiswamy, PM
    Petrella, JR
    [J]. NEURORADIOLOGY, 2004, 46 (02) : 93 - 104
  • [9] Amyloid imaging in prodromal Alzheimer's disease
    Ossenkoppele, Rik
    van Berckel, Bart N. M.
    Prins, Niels D.
    [J]. ALZHEIMERS RESEARCH & THERAPY, 2011, 3 (05)
  • [10] Amyloid imaging in prodromal Alzheimer's disease
    Rik Ossenkoppele
    Bart NM van Berckel
    Niels D Prins
    [J]. Alzheimer's Research & Therapy, 3
12345