Energetics of anaerobic degradation pathways of chlorinated aliphatic compounds

This minireview explores the energetics of the (anaerobic) oxidative and fermentative degradation of halogenated ethenes and ethanes. It is shown that these pathways are viable alternatives to the traditional routes that start with one or more reductive dechlorination steps. In contrast to reductive dehalogenation, oxidative and fermentative degradation pathways do not require an external sourer of reducing equivalents. This suggests that organisms that use these pathways are most likely to be found at high redox potentials, i.e, under conditions where competition for reducing equivalents is great.