An empirical comparison of inference using order-restricted and linear logit models for a binary response

被引:4
|
作者
Agresti, A [1 ]
Coull, BA [1 ]
机构
[1] Univ Florida, Dept Stat, Gainesville, FL 32611 USA
关键词
contingency table; isotonic regression; logistic regression; monotonicity; trend test;
D O I
10.1080/03610919808813472
中图分类号
O21 [概率论与数理统计]; C8 [统计学];
学科分类号
020208 ; 070103 ; 0714 ;
摘要
In many applications with a binary response and an ordinal or quantitative predictor, it is natural to expect the response probability to change monotonically. Two possible models are a linear model with some link, such as the linear logit model, and a more general order-restricted model that assumes monotonicity alone. The order-restricted approach is more complex to apply, and we investigate whether it may be worth the extra effort. Specifically, suppose the order restriction truly holds but a simpler linear model does not. For testing the hypothesis of independence, is there the potential of a substantive power gain by performing an order-restricted test? For estimating a set of binomial parameters, how large must the sample size be before the consistency of the order-restricted estimates and inconsistency of the model-based estimates makes a substantive difference to mean square errors? We conducted a limited simulation study comparing estimators and likelihood-ratio tests for the linear logit model and for the order-restricted model. Results suggest that order-restricted inference is preferable for moderate to large sample sizes when the true probabilities take only a couple of levels, such as in a dose-response experiment when all doses provide a uniform improvement over placebo. If the true probabilities are strictly monotone but deviate somewhat from the linear logit model, the logit-based inference is usually more powerful unless the sample size is extremely large. When the true probabilities may have slight departures from monotonicity, the order-restricted estimates often perform better, particularly for moderate to large samples.
引用
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页码:147 / 166
页数:20
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