Room Temperature Ionic Liquid as Matrix Medium for Simultaneous Determination of Residual Solvents by Static Headspace Gas Chromatography

The room temperature ionic liquid, 1-ethyl-3-methylimidazolium tetrafluoroborate, was used as the alternative solvent and coupled with static headspace gas chromatography to simultaneously determine several residual organic solvents. The analysis was carried out on a ZB-1 capillary column (60 m x 0. 53 mm, 5. 0 mu m) with programmed temperature. The headspace sampler vials was equilibrated at 100 degrees C for 20 min. An excellent separation and good linearity between the response and the concentration range of 3. 1 - 100.0 mg/L, 2.3 - 72.0 mg/L, 1. 1 - 36. 0 mg/L, 0. 6 - 20. 0 mg/L and 2. 8 - 89. 0 mg/L on acetone, tetrahydrofuran, dioxane, pyridine and toluene respectively were obtained. The average recoveries were 90.1% - 96. 9% and the RSD was less than 4. 2% (n = 9). The sensitivity of this method was improved and the detection limits were 0. 05, 0. 07, 0. 28, 0.31 and 0.04 mg/L, respectively.