An epidemic model for COVID-19 transmission in Argentina: Exploration of the alternating quarantine and massive testing strategies

被引:5
|
作者
Vassallo, Lautaro [1 ,2 ]
Perez, Ignacio A. [1 ,2 ]
Alvarez-Zuzek, Lucila G. [3 ]
Amaya, Julian [2 ]
Torres, Marcos F. [1 ,2 ]
Valdez, Lucas D. [1 ,2 ]
La Rocca, Cristian E. [1 ,2 ]
Braunstein, Lidia A. [1 ,2 ,4 ]
机构
[1] Univ Nacl Mar Plata, Inst Invest Fis Mar Plata IFIMAR, CONICET, RA-7600 Buenos Aires, Argentina
[2] Univ Nacl Mar Plata, Fac Ciencias Exactas & Nat, Dept Fis, RA-7600 Buenos Aires, Argentina
[3] Georgetown Univ, Dept Biol, Washington, DC 20057 USA
[4] Boston Univ, Phys Dept, Boston, MA 02215 USA
关键词
Mathematical epidemiology; Compartmental models; COVID-19 in Mar del Plata; Data analysis; WUHAN;
D O I
10.1016/j.mbs.2021.108664
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
The COVID-19 pandemic has challenged authorities at different levels of government administration around the globe. When faced with diseases of this severity, it is useful for the authorities to have prediction tools to estimate in advance the impact on the health system as well as the human, material, and economic resources that will be necessary. In this paper, we construct an extended Susceptible-Exposed-Infected-Recovered model that incorporates the social structure of Mar del Plata, the 4 most inhabited city in Argentina and head of the Municipality of General Pueyrredon. Moreover, we consider detailed partitions of infected individuals according to the illness severity, as well as data of local health resources, to bring predictions closer to the local reality. Tuning the corresponding epidemic parameters for COVID-19, we study an alternating quarantine strategy: a part of the population can circulate without restrictions at any time, while the rest is equally divided into two groups and goes on successive periods of normal activity and lockdown, each one with a duration of tau days. We also implement a random testing strategy with a threshold over the population. We found that tau = 7 is a good choice for the quarantine strategy since it reduces the infected population and, conveniently, it suits a weekly schedule. Focusing on the health system, projecting from the situation as of September 30, we foresee a difficulty to avoid saturation of the available ICU, given the extremely low levels of mobility that would be required. In the worst case, our model estimates that four thousand deaths would occur, of which 30% could be avoided with proper medical attention. Nonetheless, we found that aggressive testing would allow an increase in the percentage of people that can circulate without restrictions, and the medical facilities to deal with the additional critical patients would be relatively low.
引用
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页数:9
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