A catch and release program for single-stranded DNA

被引：3
|
作者：
Eoff, Robert L. [1 ]
Raney, Kevin D. [1 ]
机构：
[1] Univ Arkansas Med Sci, Dept Biochem & Mol Biol, Little Rock, AR 72205 USA
来源：
JOURNAL OF BIOLOGICAL CHEMISTRY | 2017年 / 292卷 / 31期
基金：
美国国家卫生研究院;
关键词：
BINDING-PROTEIN; COMPLEXES; MODES; SSB;
D O I：
10.1074/jbc.H117.791392
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Uncovering the mechanisms by which single-stranded binding proteins both protect and expose single-stranded DNA has important implications for our understanding of DNA replication and repair. A new study serves up a master class in developing a full kinetic model for one such protein, mtSSB, showing how DNA can be reeled in and set free to control accessibility.
引用
收藏
页码：13085 / 13086
页数：2
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