Circulating recombinant form CRF02_AG in South America

被引：29

作者：

Carrion, G ^{[6
]}

Hierholzer, J

Montano, S

Alava, A

Perez, J

Guevara, A

Laguna-Torres, V

Mosquera, C

Russell, K

Cruz, C

Chauca, G

Kochel, T

Birx, DL

Sanchez, JL

Carr, JK

机构：

[1] Henry M Jackson Fdn, Rockville, MD 20850 USA

[2] Natl Inst Hyg, Guayaquil, Ecuador

[3] Hosp Vozandes, Clin Invest Lab, Quito, Ecuador

[4] USN, Hlth Res Ctr, San Diego, CA 92186 USA

[5] Walter Reed Army Inst Res, Div Retrovirol, Silver Spring, MD 20910 USA

[6] Amer Embassy NMRCD, Unit 3800, APO, AA 34031 USA

来源：

AIDS RESEARCH AND HUMAN RETROVIRUSES | 2003年 / 19卷 / 04期

关键词：

D O I：

10.1089/088922203764969537

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

With the objective of monitoring the distribution of HIV-1 subtypes and circulating recombinant forms (CRFs) in South America, population-based surveillance studies were performed in seven countries. Peripheral blood mononuclear cell, filter paper, fresh blood, and cocultivation samples were collected from HIV-positive patients from Colombia, Ecuador, Peru, Bolivia, Chile, Argentina, and Uruguay, during a 7-year period (1995-2001). DNA was prepared and HIV envelope subtypes were determined by heteroduplex mobility assay and DNA sequencing from 1289 HIV-positive samples. While subtypes B and F were the most commonly observed subtypes, two CRF02_AG strains were detected, in Ecuador. This is the first report of the existence of this CRF in South America.

引用

页码：329 / 332

页数：4

共 50 条

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