Structural homology between bamboo mosaic virus and its satellite RNAs in the 5′ untranslated region

被引：15
|
作者：
Chen, Shih-Cheng [1 ]
Desprez, Adeline [1 ]
Olsthoorn, Rene C. L. [1 ]
机构：
[1] Leiden Univ, Leiden Inst Chem, Dept Mol Genet, NL-2300 RA Leiden, Netherlands
来源：
JOURNAL OF GENERAL VIROLOGY | 2010年 / 91卷
关键词：
CIS-ACTING SEQUENCES; STEM-LOOP STRUCTURE; TRIPLE-GENE-BLOCK; MINUS-STRAND RNA; FUNCTIONAL-ANALYSIS; POTEXVIRUS RNA; 5'-UNTRANSLATED REGION; POLY(A) TAIL; GENOMIC RNA; REPLICATION;
D O I：
10.1099/vir.0.015941-0
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
A structural element was identified in the 5'-proximal sequence of the bamboo mosaic virus (BaMV) RNA. Mutational analysis of the hairpin showed that disruptions of the secondary structure or substitutions of the loop sequences resulted in reduced accumulation of BaMV genomic RNA. Phylogenetic analysis further suggested the presence of structural homologues of this hairpin in all other potexviruses. In addition, remarkable structural homology was discovered between the BaMV hairpin and a stem-loop in the 5' untranslated region of satellite RNAs responsible for attenuation of BaMV in co-infected plants. The role of this homology in the helper-satellite interaction is discussed.
引用
收藏
页码：782 / 787
页数：6
相关论文
共 50 条
  • [1] Structural and functional analyses of the 3′ untranslated region of Bamboo mosaic virus satellite RNA
    Huang, Ying-Wen
    Hu, Chung-Chi
    Lin, Chih-An
    Liu, Yu-Ping
    Tsai, Ching-Hsiu
    Lin, Na-Sheng
    Hsu, Yau-Heiu
    VIROLOGY, 2009, 386 (01) : 139 - 153
  • [2] Interfering Satellite RNAs of Bamboo mosaic virus
    Lin, Kuan-Yu
    Lin, Na-Sheng
    FRONTIERS IN MICROBIOLOGY, 2017, 8
  • [3] Structural and mutational analyses of cis-acting sequences in the 5′-untranslated region of satellite RNA of bamboo mosaic potexvirus
    Annamalai, P
    Hsu, YH
    Liu, YP
    Tsai, CH
    Lin, NS
    VIROLOGY, 2003, 311 (01) : 229 - 239
  • [4] Genetic Diversity and Evolution of Satellite RNAs Associated with the Bamboo Mosaic Virus
    Wang, Ing-Nang
    Hu, Chung-Chi
    Lee, Ching-Wei
    Yen, Sih-Min
    Yeh, Wen-Bing
    Hsu, Yau-Heiu
    Lin, Na-Sheng
    PLOS ONE, 2014, 9 (10):
  • [5] Global Analyses of Small Interfering RNAs Derived from Bamboo mosaic virus and Its Associated Satellite RNAs in Different Plants
    Lin, Kuan-Yu
    Cheng, Chi-Ping
    Chang, Bill Chia-Han
    Wang, Wei-Chi
    Huang, Ying-Wen
    Lee, Yun-Shien
    Huang, Hsien-Da
    Hsu, Yau-Heiu
    Lin, Na-Sheng
    PLOS ONE, 2010, 5 (08):
  • [6] Structural and functional analysis of the 3′ untranslated region of bamboo mosaic potexvirus genomic RNA
    Cheng, CP
    Tsai, CH
    JOURNAL OF MOLECULAR BIOLOGY, 1999, 288 (04) : 555 - 565
  • [7] STRUCTURE OF THE 5'-TERMINAL UNTRANSLATED REGION OF THE GENOMIC RNAS FROM 2 STRAINS OF ALFALFA MOSAIC-VIRUS
    RAVELONANDRO, M
    GODEFROYCOLBURN, T
    PINCK, L
    NUCLEIC ACIDS RESEARCH, 1983, 11 (09) : 2815 - 2826
  • [8] STUDIES ON SEQUENCE HOMOLOGY BETWEEN RNAS OF ALFALFA MOSAIC-VIRUS
    BOL, JF
    BREDERODE, FT
    JANZE, GC
    RAUH, DK
    VIROLOGY, 1975, 65 (01) : 1 - 15
  • [9] Differential interactions of bamboo mosaic potexvirus satellite RNAs, helper virus, and host plants
    Hsu, YH
    Lee, YS
    Liu, JS
    Lin, NS
    MOLECULAR PLANT-MICROBE INTERACTIONS, 1998, 11 (12) : 1207 - 1213
  • [10] REPORT OF BAMBOO MOSAIC-VIRUS AND ITS ASSOCIATED SATELLITE RNA ON BAMBOO IN THE US
    LIN, NS
    LIN, BY
    YEH, TY
    PLANT DISEASE, 1995, 79 (12) : 1249 - 1249
12345