An aza-BODIPY based near-infrared fluorescent probe for sensitive discrimination of cysteine/homocysteine and glutathione in living cells

被引：96
|
作者：
Xiang, Hui-Jing [1 ,2 ]
Huijun Phoebe Tham [1 ]
Minh Duc Nguyen [1 ]
Phua, Soo Zeng Fiona [1 ]
Lim, Wei Qi [1 ]
Liu, Jin-Gang [2 ]
Zhao, Yanli [1 ,3 ]
机构：
[1] Nanyang Technol Univ, Sch Phys & Math Sci, Div Chem & Biol Chem, 21 Nanyang Link, Singapore 637371, Singapore
[2] East China Univ Sci & Technol, Sch Chem & Mol Engn, Key Lab Adv Mat, Shanghai 200237, Peoples R China
[3] Nanyang Technol Univ, Sch Mat Sci & Engn, 50 Nanyang Ave, Singapore 639798, Singapore
来源：
CHEMICAL COMMUNICATIONS | 2017年 / 53卷 / 37期
关键词：
DIFFERENT EMISSION CHANNELS; PLASMA HOMOCYSTEINE; CYSTEINE DEFICIENCY; SELECTIVE DETECTION; DYES; DISEASE; THIOLS; SENSOR; GSH; FUNCTIONALIZATION;
D O I：
10.1039/c7cc01814b
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Discriminative detection of glutathione (GSH) from cysteine/homocysteine (Cys/Hcy) is achieved through two emission channel analysis using a stable, highly sensitive, and selective near-infrared fluorescent probe that bears 7-nitrobenzo-2-oxa-1,3-diazole and aza-BODIPY units. The probe was successfully applied for simultaneous determination of GSH and Cys/Hcy in living cells.
引用
收藏
页码：5220 / 5223
页数：4
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