Insights into the substrate specificity of creatine kinase through the mutagenesis of two active-site residues

被引：0
|
作者：
Novak, WRP [1 ]
Babbitt, P [1 ]
机构：
[1] Univ Calif San Francisco, Dept Biopharmaceut Sci, San Francisco, CA 94143 USA
来源：
FASEB JOURNAL | 2003年 / 17卷 / 04期
关键词：
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页码：A152 / A152
页数：1
相关论文
共 50 条
  • [1] Control of substrate specificity by active-site residues in nitrobenzene dioxygenase
    Ju, KS
    Parales, RE
    [J]. APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2006, 72 (03) : 1817 - 1824
  • [2] Mutagenesis of two acidic active site residues in human muscle creatine kinase: Implications for the catalytic mechanism
    Cantwell, JS
    Novak, WR
    Wang, PF
    McLeish, MJ
    Kenyon, GL
    Babbitt, PC
    [J]. BIOCHEMISTRY, 2001, 40 (10) : 3056 - 3061
  • [3] COMBINATORIAL MUTAGENESIS OF ACTIVE-SITE RESIDUES OF ENZYMES
    OSUNA, J
    FLORES, H
    SOBERON, X
    [J]. PROTEIN ENGINEERING, 1993, 6 : 48 - 48
  • [4] THE ACTIVE-SITE SUBSTRATE-SPECIFICITY OF PROTEIN-KINASE-C
    KWON, YG
    MENDELOW, M
    LAWRENCE, DS
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1994, 269 (07) : 4839 - 4844
  • [5] MUTAGENESIS OF HUMAN ALDOSE REDUCTASE ACTIVE-SITE RESIDUES
    TARLE, I
    BORHANI, DW
    WILSON, DK
    QUIOCHO, FA
    PETRASH, JM
    [J]. FASEB JOURNAL, 1993, 7 (07): : A1063 - A1063
  • [6] CREATINE-KINASE ACTIVE-SITE MUTAGENESIS - SUBUNIT MODULATION OF DIMERIC ENZYME-ACTIVITY
    LIN, LJ
    PERRYMAN, MB
    FRIEDMAN, D
    JANSSON, E
    ROBERTS, R
    MA, TS
    [J]. CIRCULATION, 1992, 86 (04) : 350 - 350
  • [7] HETEROGENEOUS FLEXIBILITIES OF THE ACTIVE-SITE DOMAINS OF HOMODIMERIC CREATINE-KINASE - EFFECT OF SUBSTRATE
    GROSSMAN, SH
    FRANCE, RM
    MATTHEIS, JR
    [J]. BIOCHIMICA ET BIOPHYSICA ACTA, 1992, 1159 (01) : 29 - 36
  • [8] Changing the substrate specificity of creatine kinase from creatine to glycocyamine: Evidence for a highly evolved active site
    Jourden, Michael J.
    Clarke, Callisia N.
    Palmer, Allyson K.
    Barth, Emily J.
    Prada, Rebecca C.
    Hale, Robyn N.
    Fraga, Dean
    Snider, Mark J.
    Edmiston, Paul L.
    [J]. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS, 2007, 1774 (12): : 1519 - 1527
  • [9] ARGININE AT ACTIVE-SITE OF ENZYMES - CREATINE-KINASE
    BORDERS, CL
    RIORDAN, JF
    [J]. FEDERATION PROCEEDINGS, 1975, 34 (03) : 647 - 647
  • [10] Changing the Substrate Specificity of Creatine Kinase from Creatine to Glycocyamine: Evidence for a Highly Evolved Active Site
    Barth, Emily J.
    Fraga, Dean
    Edmiston, Paul L.
    [J]. FASEB JOURNAL, 2008, 22
12345