Methods for the synthesis of aza(deaza)xanthines as a basis of biologically active compounds

被引：5

作者：

Babkov, D. A. ^{[1
]}

Geisman, A. N. ^{[1
]}

Khandazhinskaya, A. L. ^{[2
]}

Novikov, M. S. ^{[1
]}

机构：

[1] Volgograd State Med Univ, Pl Payshikh Bortsov 1, Volgograd 400131, Russia

[2] Russian Acad Sci, Engelhardt Inst Mol Biol, Ul Vavilova 32, Moscow 119991, Russia

来源：

RUSSIAN CHEMICAL REVIEWS | 2016年 / 85卷 / 03期

基金：

俄罗斯基础研究基金会;

关键词：

ONE-POT SYNTHESIS; PURINE NUCLEOSIDE PHOSPHORYLASE; REGIOSELECTIVE N-ALKYLATION; PYRIMIDINE-DERIVATIVES; HETEROCYCLISCHEN REIHE; CONVENIENT SYNTHESIS; HEILMITTELCHEMISCHE STUDIEN; PHARMACOLOGICAL-PROPERTIES; 1,3-DIPOLAR CYCLOADDITION; AZAPURINE NUCLEOSIDES;

D O I：

10.1070/RCR4496

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The review covers methods for the synthesis of aza(deaza)xanthines, i.e., fused pyrrolo-, pyrazolo- and triazolopyrimidine heterocyclic systems, which are common core structures of various biologically active compounds. The extensive range of modern synthetic approaches is organized according to target structures and starting building blocks. The presented material is intended to benefit broad audience of specialists in the fields of organic, medicinal and pharmaceutical chemistry.

引用

页码：308 / 334

页数：27

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