Effectiveness of physiotherapy in Parkinson's disease: The feasibility of a randomised controlled trial

被引：37
|
作者：
Keus, S. H. J.
Bloem, B. R.
van Hilten, J. J.
Ashburn, A.
Munneke, M.
机构：
[1] Leiden Univ, Med Ctr, Dept Physiotherapy, NL-2300 RC Leiden, Netherlands
[2] Radboud Univ Nijmegen, Med Ctr, UMNC, Dept Neurol, Nijmegen, Netherlands
[3] Leiden Univ, Med Ctr, Dept Neurol, NL-2300 RC Leiden, Netherlands
[4] Univ Southampton, Southampton SO9 5NH, Hants, England
[5] UMCN, Res Ctr Allied Hlth Care, Dept Physiotherapy, Nijmegen, Netherlands
来源：
PARKINSONISM & RELATED DISORDERS | 2007年 / 13卷 / 02期
关键词：
feasibility studies; Parkinson disease; patient selection; physical therapy; randomised controlled trials;
D O I：
10.1016/j.parkreldis.2006.07.007
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
To study the feasibility of a large randomised controlled trial (RCT) evaluating the effectiveness of physiotherapy in Parkinson's disease (PD), 173 patients were asked to participate in a study with random allocation to best practice physiotherapy, or to no physiotherapy. The primary outcome measures were the Parkinson's disease questionnaire-39, the Parkinson activity scale, and a patient preference outcome scale (PPOS). Only 14% of the patients could be included in the study. The PPOS showed the largest effect size (0.74) with a significant group effect (p < 0.05). Specific alterations to the study design to ensure successful RCTs in this field are recommended. (c) 2006 Elsevier Ltd. All rights reserved.
引用
收藏
页码：115 / 121
页数：7
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