Recent progress in polymer-based gene delivery vectors

被引:17
|
作者
Huang, SW [1 ]
Zhuo, RX [1 ]
机构
[1] Wuhan Univ, Dept Chem, Wuhan 430072, Peoples R China
来源
CHINESE SCIENCE BULLETIN | 2003年 / 48卷 / 13期
关键词
gene delivery; gene transfer; gene therapy; polymer vector; nonviral vector;
D O I
10.1360/02wb0123
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
The gene delivery system is one of the three components of a gene medicine, which is the bottle neck of current gene therapy. Nonviral vectors offer advantages over the viral system of safety, ease of manufacturing, etc. As important nonviral vectors, polymer gene delivery systems have gained increasing attention and have begun to show increasing promising. In this review, the fundamental and recent progress of polymer-based gene delivery vectors is reviewed.
引用
收藏
页码:1304 / 1309
页数:6
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