18F-FET PET/CT in Early Subventricular Zone Recurrence of Adult Glioblastoma

被引：2

作者：

Dissaux, Gurvan ^{[1
,2
,3
]}

Dissaux, Brieg ^{[2
,4
,5
]}

Bourhis, David ^{[2
,5
,6
]}

Schick, Ulrike ^{[1
,2
,3
]}

Querellou, Solene ^{[2
,5
,6
]}

机构：

[1] Univ Hosp, Dept Radiat Oncol, Brest, France

[2] Univ Bretagne Occidentale, Brest, France

[3] INSERM 1101, LaTIM, Brest, France

[4] Univ Hosp, Dept Radiol, Brest, France

[5] EA3878 GETBO IFR 148, Brest, France

[6] Univ Hosp, Nucl Med Dept, Brest, France

来源：

CLINICAL NUCLEAR MEDICINE | 2021年 / 46卷 / 06期

关键词：

F-18-FET PET/CT; glioblastoma; recurrence; subventricular zone; MRI;

D O I：

10.1097/RLU.0000000000003639

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Glioma stem cells (GSCs) are the source of tumor recurrence in glioblastoma and are capable of whole tumor regeneration once the treatment has concluded. Compelling evidence from the last decade suggests that GSC may arise from neural stem cells residing in the adult subventricular zone (SVZ). We report the findings of an F-18-FET PET/CT showing pathological uptake in SVZ with a tumor-background ratio of greater than 1.6, giving evidence for glioblastoma recurrence. This case highlights the particular attention to be paid to the SVZ given the possible development of GSC.

引用

页码：499 / 500

页数：2

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