Adsorption mechanism of substituted pyridines on silica suspensions: An NMR study

Adsorption isotherms of 2,5-dimethylpyridine (2,5-DMP) on Aerosil 200 silica from water-2,5-DMP binary mixtures are known to exhibit special features indicative of surface phase transitions in the adsorbed layer. We have made similar observations on another substituted pyridine, 2,4,6-trimethylpyridine (2,4,6-TMP). By using ID and 2D NMR spectroscopy, we investigated adsorbed layers on silica in suspension in water/substituted-pyridine mixtures and demonstrated the existence of adsorbed species specific signals. Comparison of signals with those displayed on NMR spectra of liquid binary mixtures under various pH conditions rules out adsorption via interaction of the surface silanol group and the lone electron pair of the nitrogen atom. A mechanism of adsorption through the interaction of surface siloxane oxygen and the aromatic pi-system is proposed; it is consistent with both thermodynamic measurements and stacking of substituted pyridines within the adsorbed layer.